Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | TOP2A | P11388 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5320049 | 0.83 | ADRB2 (0.52) | PPARGCYP2D6ADRB2ADRB1ADRB3 | |
| SCHEMBL31031155 | 0.82 | PPARG (0.78) | PPARGADORA3L3MBTL1 | |
| SCHEMBL4258431 | 0.82 | ADRB2 (0.49) | PPARGCYP2D6ADRB2ADRB1ADRB3 | |
| SCHEMBL4258433 | 0.82 | ADRB2 (0.49) | PPARGCYP2D6ADRB2ADRB1ADRB3 | |
| SCHEMBL5320677 | 0.81 | MAOA (0.54) | PPARGADORA3CYP2D6TOP2A | |
| SCHEMBL7551823 | 0.80 | PPARG (0.92) | PPARGADORA3L3MBTL1 | |
| SCHEMBL30424171 | 0.79 | PPARG (0.69) | PPARGADORA3L3MBTL1 | |
| SCHEMBL16151312 | 0.79 | PPARG (0.71) | PPARGADORA3L3MBTL1 | |
| SCHEMBL3982524 | 0.76 | PPARG (0.67) | PPARGADORA3CYP2D6 | |
| SCHEMBL7554294 | 0.76 | PPARG (0.67) | PPARGADORA3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2057137-A1 | R-(-) / S-(+)-7-[3-N-SUBSTITUTED AMINO-2-HYDROXYPROPOXY]FLAVONES | Council of Scientific and Industrial Research (IN) | 2009-05-13 | — | — | EP | disclosed |
| WO-2008018089-A1 | R-(-) / S-(+)-7-[3-N-SUBSTITUTED AMINO-2-HYDROXYPROPOXY] FLAVONES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2008-02-14 | — | — | WO | disclosed |