Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4258431 | 1.00 | ADRB2 (0.49) | ADRB2ADRB1ADRB3ABCG2CYP2D6 | |
| SCHEMBL5320049 | 0.93 | ADRB2 (0.52) | ADRB2ADRB1ADRB3ABCG2CYP2D6 | |
| SCHEMBL4082991 | 0.82 | PPARG (0.60) | ADRB2ADRB1ADRB3CYP2D6ITGB3 | |
| SCHEMBL1483979 | 0.81 | ADRB2 (0.52) | ADRB2ADRB1ADRB3CYP2D6ITGB3 | |
| SCHEMBL1483981 | 0.81 | ADRB2 (0.52) | ADRB2ADRB1ADRB3CYP2D6ITGB3 | |
| SCHEMBL1483974 | 0.81 | ADRB2 (0.52) | ADRB2ADRB1ADRB3CYP2D6ITGB3 | |
| SCHEMBL14293136 | 0.79 | ADRB2 (0.49) | ADRB2ADRB1ADRB3CYP2D6 | |
| SCHEMBL5320651 | 0.76 | MEN1 (0.53) | ABCG2CYP2D6MEN1KMT2AMAOB | |
| SCHEMBL4407561 | 0.76 | CYP1A1 (0.48) | ADRB2ADRB1ADRB3CYP2D6ITGB3 | |
| SCHEMBL20169801 | 0.76 | ABCG2 (0.59) | ABCG2MEN1KMT2AMAOBPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2057137-A1 | R-(-) / S-(+)-7-[3-N-SUBSTITUTED AMINO-2-HYDROXYPROPOXY]FLAVONES | Council of Scientific and Industrial Research (IN) | 2009-05-13 | — | — | EP | disclosed |
| WO-2008018089-A1 | R-(-) / S-(+)-7-[3-N-SUBSTITUTED AMINO-2-HYDROXYPROPOXY] FLAVONES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2008-02-14 | — | — | WO | disclosed |