Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4258433 | 0.93 | ADRB2 (0.49) | ADRB2ADRB1ADRB3CYP2D6ITGB3 | |
| SCHEMBL4258431 | 0.93 | ADRB2 (0.49) | ADRB2ADRB1ADRB3CYP2D6ITGB3 | |
| SCHEMBL20169801 | 0.83 | ABCG2 (0.59) | MEN1KMT2AABCG2PPARGABCB1 | |
| SCHEMBL4082991 | 0.83 | PPARG (0.60) | ADRB2ADRB1ADRB3CYP2D6ITGB3 | |
| SCHEMBL5320651 | 0.81 | MEN1 (0.53) | CYP2D6MEN1KMT2AABCG2ABCB1 | |
| SCHEMBL1483979 | 0.81 | ADRB2 (0.52) | ADRB2ADRB1ADRB3CYP2D6ITGB3 | |
| SCHEMBL1483981 | 0.81 | ADRB2 (0.52) | ADRB2ADRB1ADRB3CYP2D6ITGB3 | |
| SCHEMBL1483974 | 0.81 | ADRB2 (0.52) | ADRB2ADRB1ADRB3CYP2D6ITGB3 | |
| SCHEMBL4407561 | 0.79 | CYP1A1 (0.48) | ADRB2ADRB1ADRB3CYP2D6ITGB3 | |
| SCHEMBL14293136 | 0.78 | ADRB2 (0.49) | ADRB2ADRB1ADRB3CYP2D6ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807408-A1 | OXY SUBSTITUTED FLAVONES AS ANTIHYPERGLYCEMIC AND ANTIDYSLIPIDEMIC AGENTS | Council of Scientific and Industrial Research (IN) | 2007-07-18 | — | — | EP | claimed |
| WO-2006040621-A1 | OXY SUBSTITUTED FLAVONES AS ANTIHYPERGLYCEMIC AND ANTIDYSLIPIDEMIC AGENTS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-04-20 | — | — | WO | claimed |