Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.33 |
| ▸ | MARK4 | Q96L34 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.32 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3762542 | 0.74 | EGFR (0.49) | — | |
| SCHEMBL3760932 | 0.74 | CASP1 (0.51) | — | |
| SCHEMBL3760931 | 0.70 | PDE5A (0.54) | MEN1KMT2ALMNAALDH1A1PDE5A | |
| SCHEMBL3762539 | 0.70 | PDE5A (0.54) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL31146637 | 0.68 | GOT1 (0.38) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL3762536 | 0.66 | GPR139 (0.36) | MAOBMARK4MEN1KMT2ALMNA | |
| SCHEMBL4951818 | 0.62 | MAOB (0.73) | MAOBALDH1A1TAAR1 | |
| SCHEMBL8755 | 0.62 | MAOB (0.73) | MAOBALDH1A1TAAR1 | |
| SCHEMBL5508681 | 0.61 | MAOB (0.63) | MAOBLMNATAAR1 | |
| SCHEMBL29838709 | 0.60 | QPCT (0.39) | KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1833803-A4 | PHARMACEUTICAL COMPOUNDS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF | MYRIAD GENETICS INC (US) | 2009-08-05 | — | — | EP | disclosed |
| EP-1833803-A2 | PHARMACEUTICAL COMPOUNDS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF | MYRIAD GENETICS, INC. (US) | 2007-09-19 | — | — | EP | disclosed |
| WO-2006074223-A2 | PHARMACEUTICAL COMPOUNDS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF | MYRIAD GENETICS, INC. (US) | 2006-07-13 | — | — | WO | disclosed |