Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13633146 | 0.89 | SCN8A (0.35) | HDAC1CA2AKT1VSIR | |
| Hydrochloric Acid SCHEMBL4490670 | 0.88 | SCN8A (0.35) | HDAC1CA2AKT1VSIR | |
| SCHEMBL4074510 | 0.81 | AKT1 (0.36) | HDAC1CA2AKT1VSIR | |
| SCHEMBL4081718 | 0.80 | AKT1 (0.35) | HDAC1AKT1VSIR | |
| SCHEMBL4071465 | 0.80 | CSNK2A1 (0.40) | HDAC1CA2AKT1VSIR | |
| SCHEMBL4080115 | 0.76 | AKT1 (0.35) | HDAC1AKT1VSIR | |
| SCHEMBL4082823 | 0.75 | AKT1 (0.39) | HDAC1AKT1VSIR | |
| SCHEMBL4256175 | 0.72 | AKT1 (0.38) | HDAC1AKT1VSIR | |
| SCHEMBL4345238 | 0.65 | IDO1 (0.50) | — | |
| SCHEMBL24609206 | 0.65 | RXRA (0.41) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2084127-A1 | DIARYL, DIPYRIDINYL AND ARYL-PYRIDINYL DERIVATIVES AND USES THEREOF | Pfizer Products Inc. (US) | 2009-08-05 | — | — | EP | claimed |
| WO-2008059335-A1 | DIARYL, DIPYRIDINYL AND ARYL-PYRIDINYL DERIVATIVES AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2008-05-22 | — | — | WO | claimed |