Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
| ▸ | WNT3A | P56704 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4085193 | 0.86 | ALOX15 (0.55) | ACHEABL1RIN1KDM4ETDP1 | |
| SCHEMBL4084211 | 0.83 | ACHE (0.57) | ACHEABL1RIN1KDM4ETDP1 | |
| SCHEMBL4092051 | 0.81 | ELANE (0.52) | ELANEPOLBL3MBTL1ALDH1A1MAPT | |
| SCHEMBL4083746 | 0.81 | POLB (0.50) | ACHEABL1RIN1KDM4ETDP1 | |
| SCHEMBL4085618 | 0.80 | ALOX15 (0.54) | ACHEABL1RIN1KDM4ETDP1 | |
| SCHEMBL13765410 | 0.79 | ACHE (0.52) | ACHEABL1RIN1KDM4ETDP1 | |
| SCHEMBL4085598 | 0.78 | ACHE (0.50) | ACHEABL1RIN1KDM4ETDP1 | |
| SCHEMBL4085034 | 0.78 | TOP2A (0.56) | ACHEABL1RIN1KDM4ETDP1 | |
| SCHEMBL15093413 | 0.77 | GAA (0.53) | ACHETDP1ALDH1A1HTTGAA | |
| SCHEMBL4090515 | 0.77 | TOP2A (0.62) | ACHEABL1RIN1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2237683-B1 | METHOD OF FLAVORING | GIVAUDAN SA (CH) | 2015-11-11 | — | — | EP | claimed |
| EP-2237683-B1 | METHOD OF FLAVORING | GIVAUDAN SA (CH) | 2015-11-11 | — | — | EP | disclosed |
| US-20130177688-A1 | Method of Flavoring | GIVAUDAN S.A. (CH) | 2013-07-11 | — | — | US | disclosed |
| US-20130177688-A1 | Method of Flavoring | GIVAUDAN S.A. (CH) | 2013-07-11 | — | — | US | disclosed |
| US-20130177688-A1 | Method of Flavoring | GIVAUDAN S.A. (CH) | 2013-07-11 | — | — | US | disclosed |
| US-20090186138-A1 | Method of Flavoring | GIVAUDAN SA (CH) | 2009-07-23 | — | — | US | disclosed |
| US-20090186138-A1 | Method of Flavoring | GIVAUDAN SA (CH) | 2009-07-23 | — | — | US | disclosed |
| US-20090186138-A1 | Method of Flavoring | GIVAUDAN SA (CH) | 2009-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090186138-A1 | Method of Flavoring | TAS2R5, TAS2R50, TAS2R10 | ELANE 2766/4885ACHE 3270/4885ABL1 2986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.