SCHEMBL4084675

SCHEMBL4084675

C=CCNc1cccnc1CC=C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RRM2 P31350 1/20 0.47
SLC2A1 P11166 1/20 0.39
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38
SMN1; SMN2 Q16637 4/20 0.37
RAB9A P51151 3/20 0.37
MAPT P10636 2/20 0.37
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
GAA P10253 1/20 0.37
NPC1 O15118 1/20 0.36
SUMO3 P55854 1/20 0.36
SUMO2 P61956 1/20 0.36
SUMO1 P63165 1/20 0.36
KDM4E B2RXH2 3/20 0.35
HTT P42858 2/20 0.35
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8999006 0.77 RRM2 (0.48) RRM2SLC2A1CA12CA1CA2
SCHEMBL15467305 0.77 RRM2 (0.48) RRM2SLC2A1CA12CA1CA2
SCHEMBL27530818 0.77 RRM2 (0.48) RRM2SLC2A1CA12CA1CA2
SCHEMBL26093725 0.76 SHMT2 (0.39) SMN1; SMN2RAB9AMAPTKMT2AMEN1
SCHEMBL17629027 0.75 MEN1 (0.52) RRM2SMN1; SMN2MAPTKMT2AMEN1
SCHEMBL17629029 0.73 MEN1 (0.53) RRM2SMN1; SMN2RAB9AMAPTKMT2A
SCHEMBL2163151 0.73 ALDH1A1 (0.54) RRM2SLC2A1SMN1; SMN2RAB9AMAPT
SCHEMBL4784858 0.72 ALDH1A1 (0.44) RRM2SLC2A1CA12CA1CA2
SCHEMBL7152310 0.72 SLC2A1 (0.52) RRM2SLC2A1CA12CA1CA2
SCHEMBL4755263 0.72 RRM2 (0.47) RRM2CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104093560-B Thin-film laminate 日本曹达株式会社 2016-10-26 CN disclosed
CN-104093560-A Thin-film laminate NIPPON SODA CO 2014-10-08 CN disclosed
CN-101400640-B Method for producing 1,2-phenylethane compound using atom transfer radical coupling reaction NIPPON SODA CO 2013-05-08 CN disclosed
CN-101087813-B Method for removing metal and method for producing polymer NIPPON SODA CO 2010-05-12 CN disclosed
CN-100594184-C Dispersion of titanium oxide particles, titanium oxide thin film, solution for forming organic functional film, substrate having organic functional film formed thereon and method for producing same NIPPON SODA CO 2010-03-17 CN disclosed
CN-100551944-C Polymer solid electrolyte NIPPON SODA CO (JP) 2009-10-21 CN disclosed
US-7579459-B2 Activator bound solid supports for nucleic acid synthesis via the phosphoramidite approach NGO NAM Q 2009-08-25 US disclosed
CN-101400640-A Method for producing 1,2-phenylethane compound using atom transfer radical coupling reaction NIPPON SODA CO (JP) 2009-04-01 CN disclosed
CN-101115682-A Dispersion of titanium oxide particles, titanium oxide thin film, solution for forming organic functional film, substrate having organic functional film formed thereon and method for producing same NIPPON SODA CO (JP) 2008-01-30 CN disclosed
CN-101087813-A Method for removing metal and method for producing polymer NIPPON SODA CO (JP) 2007-12-12 CN disclosed
US-20070135626-A1 Activator bound solid supports for nucleic acid synthesis via the phosphoramidite approach CTGEN, INC (US) 2007-06-14 US disclosed
CN-1668662-A Solid polymer electrolyte NIPPON SODA CO (JP) 2005-09-14 CN disclosed