Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 9/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4076511 | 0.82 | OPRL1 (0.59) | OPRL1OPRM1SLC6A2SLC6A4 | |
| SCHEMBL209214 | 0.80 | OPRM1 (0.42) | OPRL1OPRM1SLC6A2SLC6A4CYP2D6 | |
| SCHEMBL20866603 | 0.71 | OPRL1 (0.59) | OPRL1OPRM1SLC6A2KCNA3 | |
| SCHEMBL4079446 | 0.69 | OPRL1 (0.48) | OPRL1OPRM1 | |
| SCHEMBL249645 | 0.68 | LMNA (0.43) | OPRL1OPRM1SLC6A2SLC6A4LMNA | |
| SCHEMBL4072298 | 0.68 | OPRM1 (0.52) | OPRL1OPRM1SLC6A2SLC6A4CYP2D6 | |
| SCHEMBL21766654 | 0.68 | OPRM1 (0.52) | OPRL1OPRM1SLC6A2SLC6A4LMNA | |
| SCHEMBL21780743 | 0.68 | OPRM1 (0.46) | OPRL1OPRM1SLC6A2SLC6A4LMNA | |
| SCHEMBL209213 | 0.67 | OPRM1 (0.41) | OPRL1OPRM1SLC6A2SLC6A4CYP2D6 | |
| SCHEMBL5168924 | 0.67 | OPRM1 (0.54) | OPRL1OPRM1SLC6A2SLC6A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745010-B1 | SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2009-08-05 | — | — | EP | claimed |