Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2209619 | 1.00 | DUT (0.41) | DUTFFAR1L3MBTL1MAOAMAOB | |
| SCHEMBL17024422 | 0.99 | DUT (0.42) | DUTFFAR1L3MBTL1GRM2 | |
| SCHEMBL2205493 | 0.99 | DUT (0.42) | DUTFFAR1L3MBTL1GRM2 | |
| SCHEMBL2235448 | 0.88 | MAOA (0.39) | DUTFFAR1MAOAMAOBPRMT5 | |
| SCHEMBL2235433 | 0.88 | MAOA (0.39) | DUTFFAR1MAOAMAOBPRMT5 | |
| SCHEMBL2235442 | 0.88 | MAOA (0.39) | DUTFFAR1MAOAMAOBPRMT5 | |
| SCHEMBL2207489 | 0.85 | DUT (0.41) | DUTFFAR1L3MBTL1MAOAMAOB | |
| SCHEMBL21100523 | 0.84 | DUT (0.40) | DUTFFAR1MAOAMAOB | |
| SCHEMBL4423217 | 0.84 | SIRT2 (0.39) | DUTFFAR1L3MBTL1MAOAMAOB | |
| SCHEMBL2207890 | 0.84 | PDE4B (0.43) | FFAR1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091955-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | Acucela, Inc. (US) | 2009-08-26 | — | — | EP | disclosed |
| WO-2009045479-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. (US) | 2009-04-09 | — | — | WO | disclosed |