Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | DUT | P33316 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.37 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2207489 | 0.92 | DUT (0.41) | DUTL3MBTL1MAOAMAOBGRM2 | |
| SCHEMBL4085382 | 0.84 | DUT (0.41) | SIRT2DUTL3MBTL1MAOAMAOB | |
| SCHEMBL2209619 | 0.84 | DUT (0.41) | SIRT2DUTL3MBTL1MAOAMAOB | |
| SCHEMBL4569091 | 0.83 | PDE4B (0.43) | GRM2FFAR1 | |
| SCHEMBL2207883 | 0.83 | PDE4B (0.43) | GRM2FFAR1 | |
| SCHEMBL2207890 | 0.83 | PDE4B (0.43) | GRM2FFAR1 | |
| SCHEMBL2207879 | 0.83 | PDE4B (0.43) | GRM2FFAR1 | |
| SCHEMBL2206778 | 0.83 | MAOA (0.39) | DUTMAOAMAOBGRM2 | |
| SCHEMBL2206773 | 0.83 | MAOA (0.39) | DUTMAOAMAOBGRM2 | |
| SCHEMBL2206779 | 0.83 | MAOA (0.39) | DUTMAOAMAOBGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090326074-A1 | Alkoxy compounds for disease treatment | ACUCELA INC. (US) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090326074-A1 | Alkoxy compounds for disease treatment | ALDH1A2, CLN6, AGER | SIRT2 923/4885DUT 3010/4885L3MBTL1 2398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.