Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 4/20 | 0.57 |
| ▸ | KCNQ2 | O43526 | 4/20 | 0.57 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.57 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.57 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 3/20 | 0.48 |
| ▸ | SMO | Q99835 | 1/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | JAK1 | P23458 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3252070 | 0.88 | ULK1 (0.47) | KCNQ3KCNQ2RAB9ANPC1MAPT | |
| SCHEMBL3246091 | 0.87 | KCNH2 (0.51) | KCNQ3KCNQ2KMT2ARAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL3252697 | 0.87 | ULK1 (0.46) | KCNQ3KCNQ2RAB9ANPC1MAPT | |
| Hydrochloric Acid SCHEMBL4095369 | 0.87 | KCNQ3 (0.57) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| Hydrochloric Acid SCHEMBL3252683 | 0.86 | KCNH2 (0.50) | KCNQ3KCNQ2KMT2ARAB9ANPC1 | |
| SCHEMBL3244037 | 0.86 | KDM4E (0.45) | KCNQ3KCNQ2KMT2ARAB9ANPC1 | |
| SCHEMBL3249731 | 0.85 | KMT2A (0.59) | KCNQ3KCNQ2MEN1KMT2ARAB9A | |
| SCHEMBL3248045 | 0.85 | RORC (0.53) | — | |
| Hydrochloric Acid SCHEMBL3240697 | 0.84 | KMT2A (0.58) | KCNQ3KCNQ2MEN1KMT2ARAB9A | |
| Hydrochloric Acid SCHEMBL3252662 | 0.84 | RORC (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090197872-A1 | NOVEL 1,4-DIAZA-BICYCLO[3.2.2]NONYL PYRIMIDINYL DERIVATIVES AND THEIR MEDICAL USE | NEUROSEARCH A/S (DK) | 2009-08-06 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090197872-A1 | NOVEL 1,4-DIAZA-BICYCLO[3.2.2]NONYL PYRIMIDINYL DERIVATIVES AND THEIR MEDICAL USE | CHRNA2, CHRNA6, CHRNA3 | KCNQ3 707/4885KCNQ2 898/4885KCNE1 1454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.