SCHEMBL4085929

SCHEMBL4085929

CN1c2ccccc2N(C)c2cc(-c3ccc4c(c3)N(C)c3ccccc3N4C)ccc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.44
NOX1 Q9Y5S8 3/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
ADRA2A P08913 1/20 0.41
ADRA2B P18089 1/20 0.41
ADRA2C P18825 1/20 0.41
CHRM3 P20309 1/20 0.41
SLC6A2 P23975 1/20 0.41
HTR2C P28335 1/20 0.41
SLC6A4 P31645 1/20 0.41
DRD3 P35462 1/20 0.41
HTR2B P41595 1/20 0.41
AKT1 P31749 1/20 0.40
CHEK1 O14757 2/20 0.37
AURKA O14965 1/20 0.37
DAPK3 O43293 1/20 0.37
JAK2 O60674 1/20 0.37
PRKD3 O94806 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5069422 0.95 MAOA (0.41) MAOANOX1L3MBTL1KMT2AMEN1
SCHEMBL5068071 0.93 ALDH1A1 (0.43) MAOAL3MBTL1KMT2AMEN1CHEK1
SCHEMBL19532241 0.84 ABL1 (0.53) L3MBTL1KMT2AMEN1ABL1KDR
SCHEMBL482716 0.81 MAOA (0.60) MAOANOX1L3MBTL1KMT2AMEN1
SCHEMBL4571020 0.81 MAOA (0.60) MAOANOX1L3MBTL1KMT2AMEN1
SCHEMBL29390564 0.81 MAOA (0.60) MAOANOX1L3MBTL1KMT2AMEN1
SCHEMBL13636983 0.81
SCHEMBL19001734 0.80 OPRK1 (0.43) MAOANOX1L3MBTL1KMT2AMEN1
SCHEMBL7170986 0.80 MEN1 (0.40) MAOANOX1L3MBTL1KMT2AMEN1
SCHEMBL19540745 0.79 SCN5A (0.47) AURKAABL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3221420-B1 PHOTOCHROMIC-ELECTROCHROMIC COMPOSITIONS SWITCH MAT INC (CA) 2021-02-17 EP disclosed
US-10647913-B2 Photochromic-electrochromic compositions SWITCH MATERIALS INC. (CA) 2020-05-12 US disclosed
US-20170355901-A1 PHOTOCHROMIC-ELECTROCHROMIC COMPOSITIONS SOLUTIA CANADA INC. (CA) 2017-12-14 US disclosed
EP-3221420-A1 PHOTOCHROMIC-ELECTROCHROMIC COMPOSITIONS Switch Materials, Inc. (CA) 2017-09-27 EP disclosed
WO-2016077918-A1 PHOTOCHROMIC-ELECTROCHROMIC COMPOSITIONS SWITCH MATERIALS INC. (CA) 2016-05-26 WO disclosed
EP-1330678-B1 ELECTROCHROMIC WINDOWS AND METHOD OF MANUFACTURING THE SAME GENTEX CORP (US) 2015-09-23 EP disclosed
US-7525714-B2 Electrochromic windows and method of making the same GENTEX CORPORATION (US) 2009-04-28 US disclosed
US-20070103763-A1 ELECTROCHROMIC WINDOWS AND METHOD OF MAKING THE SAME GENTEX CORPORATION 2007-05-10 US disclosed
US-7154657-B2 Electrochromic windows and method of making the same GENTEX CORPORATION (US) 2006-12-26 US disclosed
US-20060077511-A1 Electrochromic windows and method of making the same POLL DAVID L 2006-04-13 US disclosed
US-20050117193-A1 ELECTROCHROMIC WINDOWS AND METHOD OF MAKING THE SAME POLL DAVID L (US) 2005-06-02 US disclosed
US-6842276-B2 Electrochromic windows and method of making the same GENTEX CORPORATION (US) 2005-01-11 US disclosed
US-20040095631-A1 Electrochromic windows and method of making the same POLL DAVID L (US) 2004-05-20 US disclosed
US-6671080-B2 Electrochromic windows and method of making the same GENTEX CORPORATION 2003-12-30 US disclosed
US-20030137715-A1 Electrochromic windows and method of making the same POLL DAVID L (US) 2003-07-24 US disclosed
US-6594067-B2 Electrochromic windows and method of making the same GENTEX CORPORATION 2003-07-15 US disclosed
US-6560004-B2 Coupled electrochromic compounds with photostable dication oxidation states GENTEX CORPORATION 2003-05-06 US disclosed
US-20020075552-A1 Electrochromic windows and method of making the same POLL DAVID L (US) 2002-06-20 US disclosed
US-6407847-B1 Electrochromic medium having a color stability GENTEX CORPORATION 2002-06-18 US disclosed
US-6249369-B1 Coupled electrochromic compounds with photostable dication oxidation states GENTEX CORPORATION 2001-06-19 US disclosed