SCHEMBL5068071

SCHEMBL5068071

CN1c2ccc(-c3ccccc3)cc2N(C)c2ccc(-c3ccccc3)cc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
ALOX5 P09917 1/20 0.43
CHEK1 O14757 1/20 0.40
AURKA O14965 1/20 0.40
DAPK3 O43293 1/20 0.40
JAK2 O60674 1/20 0.40
PRKD3 O94806 1/20 0.40
MAP4K4 O95819 1/20 0.40
PAK4 O96013 1/20 0.40
ABL1 P00519 1/20 0.40
NTRK1 P04629 1/20 0.40
LCK P06239 1/20 0.40
FYN P06241 1/20 0.40
CSF1R P07333 1/20 0.40
RET P07949 1/20 0.40
IGF1R P08069 1/20 0.40
MET P08581 1/20 0.40
PDGFRB P09619 1/20 0.40
PIM1 P11309 1/20 0.40
FGFR1 P11362 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5069422 0.98 MAOA (0.41) ALDH1A1ALOX5CHEK1AURKADAPK3
SCHEMBL4085929 0.93 MAOA (0.44) ALOX5CHEK1AURKADAPK3JAK2
SCHEMBL20618844 0.86 OPRK1 (0.45) ALDH1A1ALOX5CHEK1AURKADAPK3
SCHEMBL16810642 0.83 MAOA (0.57) ALDH1A1ALOX5MAOAMEN1LMNA
SCHEMBL19532241 0.82 ABL1 (0.53) ALDH1A1ABL1KDRDYRK1AESR2
SCHEMBL13507589 0.82 MEN1 (0.38) ALDH1A1ALOX5CHEK1AURKADAPK3
SCHEMBL19001734 0.82 OPRK1 (0.43) ALDH1A1ALOX5CHEK1AURKADAPK3
SCHEMBL2493673 0.81 MAOA (0.55) ALOX5MAOAMEN1LMNAMAPT
SCHEMBL16544662 0.81 CYP11B1 (0.41) ALDH1A1ALOX5MEN1KMT2AKDM4E
SCHEMBL13326565 0.81 CYP11B1 (0.43) ACVR1MAPTMAPK1CYP1A2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7450293-B2 Electrochromic salts, solutions, and devices LOS ALAMOS NATIONAL SECURITY, LLC (US) 2008-11-11 US claimed
US-7436570-B2 Electrochromic salts, solutions, and devices LOS ALAMOS NATIONAL SECURITY, LLC (US) 2008-10-14 US claimed
EP-1457813-B1 An improved electrochromic medium capable of producing a pre-selected color GENTEX CORP (US) 2007-01-24 EP claimed
US-20050151467-A1 Electrochromic salts, solutions, and devices TRIAD NATIONAL SECURITY, LLC 2005-07-14 US claimed
US-20050116627-A1 Electrochromic salts, solutions, and devices TRIAD NATIONAL SECURITY, LLC 2005-06-02 US claimed
EP-1457813-A2 An improved electrochromic medium capable of producing a pre-selected color Gentex Corporation (US) 2004-09-15 EP claimed
EP-0972227-B1 AN IMPROVED ELECTROCHROMIC MEDIUM CAPABLE OF PRODUCING A PRE-SELECTED COLOR GENTEX CORP (US) 2004-07-14 EP claimed
WO-2004000800-A2 ELECTROCHROMIC SALTS, SOLUTIONS, AND DEVICES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2003-12-31 WO claimed
US-20030234379-A1 Electrochromic salts, solutions, and devices LOS ALAMOS NATIONAL SECURITY, LLC 2003-12-25 US claimed
US-6020987-A Electrochromic medium capable of producing a pre-selected color GENTEX CORPORATION (US) 2000-02-01 US claimed
US-5998617-A MIXTURE OF ELECTROACTIVE MATERIALS AT PRESELECTIVE CONCENTRATION; GRAY COLOR GENTEX CORPORATION (US) 1999-12-07 US claimed
US-11319483-B2 Organic compound, electrochromic element containing the same, optical filter, lens unit, imaging device, and window material CANON KABUSHIKI KAISHA (JP) 2022-05-03 US disclosed
EP-3320392-B1 ELECTROCHROMIC ELEMENT, OPTICAL FILTER, LENS UNIT, IMAGING APPARATUS, AND WINDOW MEMBER CANON KK (JP) 2021-10-27 EP disclosed
EP-3221420-B1 PHOTOCHROMIC-ELECTROCHROMIC COMPOSITIONS SWITCH MAT INC (CA) 2021-02-17 EP disclosed
US-10647913-B2 Photochromic-electrochromic compositions SWITCH MATERIALS INC. (CA) 2020-05-12 US disclosed
US-6037471-A FOR ELECTROCHROMIC MIRRORS FOR MOTOR VEHICLES GENTEX CORPORATION (US) 2000-03-14 US disclosed
US-6020987-A Electrochromic medium capable of producing a pre-selected color GENTEX CORPORATION (US) 2000-02-01 US disclosed
EP-0972227-A1 AN IMPROVED ELECTROCHROMIC MEDIUM CAPABLE OF PRODUCING A PRE-SELECTED COLOR GENTEX CORPORATION (US) 2000-01-19 EP disclosed
US-5998617-A MIXTURE OF ELECTROACTIVE MATERIALS AT PRESELECTIVE CONCENTRATION; GRAY COLOR GENTEX CORPORATION (US) 1999-12-07 US disclosed
WO-1998044384-A1 AN IMPROVED ELECTROCHROMIC MEDIUM CAPABLE OF PRODUCING A PRE-SELECTED COLOR GENTEX CORPORATION (US) 1998-10-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050151467-A1 Electrochromic salts, solutions, and devices F8, ETV6, HCN4 ALDH1A1 4195/4885ALOX5 4716/4885CHEK1 3142/4885
US-11319483-B2 Organic compound, electrochromic element containing the same, optical filter, lens unit, imaging device, and window material OR10J3, EBPL, ARL1 ALDH1A1 1980/4885ALOX5 319/4885CHEK1 2614/4885
US-20050116627-A1 Electrochromic salts, solutions, and devices F8, ETV6, HCN4 ALDH1A1 4195/4885ALOX5 4716/4885CHEK1 3142/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.