Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.75 |
| ▸ | HTT | P42858 | 3/20 | 0.75 |
| ▸ | MAPT | P10636 | 3/20 | 0.75 |
| ▸ | HPGD | P15428 | 3/20 | 0.75 |
| ▸ | ESR1 | P03372 | 1/20 | 0.75 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.75 |
| ▸ | PKM | P14618 | 1/20 | 0.75 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.74 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ELANE | P08246 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NOS3 | P29474 | 1/20 | 0.50 |
| ▸ | NOS1 | P29475 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Hydroxyacetophenone SCHEMBL9034324 | 0.98 | LMNA (0.71) | LMNAHTTMAPTHPGDESR1 | |
| SCHEMBL22365141 | 0.93 | HSD17B1 (0.87) | LMNAHTTMAPTHPGDESR1 | |
| SCHEMBL21935943 | 0.93 | HSD17B1 (0.87) | LMNAHTTMAPTHPGDESR1 | |
| 4-Hydroxyacetophenone SCHEMBL8934912 | 0.92 | HSD17B1 (0.85) | LMNAHTTMAPTHPGDESR1 | |
| 4-Hydroxyacetophenone SCHEMBL40866 | 0.92 | HSD17B1 (0.85) | LMNAHTTMAPTHPGDESR1 | |
| Benzophenone SCHEMBL28321900 | 0.91 | MAPT (0.70) | LMNAHTTMAPTHPGDESR1 | |
| 4-Hydroxyacetophenone SCHEMBL9480590 | 0.90 | HSD17B1 (0.81) | LMNAHTTMAPTHPGDESR1 | |
| 4-Hydroxyacetophenone SCHEMBL31385561 | 0.90 | HSD17B1 (0.81) | LMNAHTTMAPTHPGDESR1 | |
| 4-Hydroxyacetophenone SCHEMBL8744798 | 0.90 | HSD17B1 (0.81) | LMNAHTTMAPTHPGDESR1 | |
| 4-Hydroxyacetophenone SCHEMBL28895846 | 0.90 | HSD17B1 (0.81) | LMNAHTTMAPTHPGDESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2553011-B1 | POLYMER COMPOSITIONS COMPRISING CORE/SHELL PARTICLES | SOLVAY (BE) | 2014-12-31 | — | — | EP | disclosed |
| WO-2011117410-A1 | POLYMER COMPOSITIONS COMPRISING CORE/SHELL PARTICLES | SOLVAY SA (BE) | 2011-09-29 | — | — | WO | disclosed |
| US-6242654-B1 | REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND | MITSUI CHEMICALS, INC. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-1013629-A1 | Preparation process of fluorine subsituted aromatic compound | Mitsui Chemicals, Inc. (JP) | 2000-06-28 | — | — | EP | disclosed |