SCHEMBL4087302

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13722427	0.87	LMNA (0.42)	LMNALOXL2TSHRPOLBKMT2A
	SCHEMBL9906216	0.75	TSHR (0.43)	LMNALOXL2TSHRPOLBKMT2A
	SCHEMBL7103432	0.70	LMNA (0.56)	LMNALOXL2TSHRPOLBKMT2A
	SCHEMBL10866449	0.69	LMNA (0.55)	LMNALOXL2TSHRPOLBKMT2A
	SCHEMBL28733001	0.69	LMNA (0.51)	LMNALOXL2TSHRPOLBKMT2A
	SCHEMBL10898608	0.68	PGK1 (0.35)	ALDH1A1L3MBTL1
	SCHEMBL99564	0.67	LOXL2 (0.61)	LOXL2TSHRPOLBKMT2AMEN1
	SCHEMBL11369488	0.67	LOXL2 (0.57)	LMNALOXL2TSHRPOLBKMT2A
	SCHEMBL2325845	0.67	LMNA (0.53)	LMNALOXL2TSHRPOLBKMT2A
	SCHEMBL16093322	0.64	LOXL2 (0.53)	LMNALOXL2TSHRPOLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.