SCHEMBL4088560

SCHEMBL4088560

FC(F)(F)c1cccc(NNc2ccccc2C(F)(F)F)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.54
ALDH1A1 P00352 4/20 0.54
RAB9A P51151 3/20 0.54
GAA P10253 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
RXFP1 Q9HBX9 7/20 0.53
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
HTT P42858 2/20 0.47
IDH2 P48735 1/20 0.47
KDR P35968 1/20 0.47
GRIK1 P39086 1/20 0.46
TDP1 Q9NUW8 2/20 0.45
NPSR1 Q6W5P4 1/20 0.45
YAP1 P46937 1/20 0.45
TEAD4 Q15561 1/20 0.45
TEAD2 Q15562 1/20 0.45
POLB P06746 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
NPC1 O15118 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29748950 0.84 MAPT (0.58) MAPTALDH1A1RAB9AGAASMN1; SMN2
SCHEMBL2925587 0.84 MAPT (0.58) MAPTALDH1A1RAB9AGAASMN1; SMN2
SCHEMBL22169162 0.82 ALDH1A1 (0.53) ALDH1A1GAASMN1; SMN2MEN1KMT2A
SCHEMBL23581575 0.80 POLB (0.64) MAPTALDH1A1GAASMN1; SMN2MEN1
Methyl Alcohol SCHEMBL28589867 0.77 CRHR1 (0.49) ALDH1A1RAB9AGAAMEN1KMT2A
SCHEMBL24732382 0.77 KDR (0.73) MAPTALDH1A1RAB9AGAARXFP1
SCHEMBL1921484 0.77 MAPT (0.77) MAPTALDH1A1RAB9AGAASMN1; SMN2
SCHEMBL4093215 0.77 MAPT (0.51) MAPTALDH1A1RAB9AGAASMN1; SMN2
Toluene SCHEMBL28269609 0.75 ALDH1A1 (0.46) MAPTALDH1A1GAAMEN1KMT2A
SCHEMBL20320380 0.73 IDH2 (0.57) MAPTALDH1A1RAB9AGAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996018625-A1 METHOD FOR OBTAINING A NOVEL RANGE OF SYNTHETIC PREPARATIONS FOR PHYTOSANITARY USE KERSERHO FRANCOIS MARIE (FR) 1996-06-20 WO claimed
EP-1113026-B1 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL CO (JP) 2009-12-09 EP disclosed
EP-2048170-A2 Second catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer Sumitomo Chemical Company, Limited (JP) 2009-04-15 EP disclosed
EP-2048168-A2 Process for producing catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer Sumitomo Chemical Company, Limited (JP) 2009-04-15 EP disclosed
EP-2048167-A2 First catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer Sumitomo Chemical Company, Limited (JP) 2009-04-15 EP disclosed
EP-2048169-A2 Third catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer Sumitomo Chemical Company, Limited (JP) 2009-04-15 EP disclosed
WO-1996018625-A1 METHOD FOR OBTAINING A NOVEL RANGE OF SYNTHETIC PREPARATIONS FOR PHYTOSANITARY USE KERSERHO FRANCOIS MARIE (FR) 1996-06-20 WO disclosed