Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.71 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.71 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Picolinic Acid SCHEMBL25335049 | 0.93 | L3MBTL1 (0.77) | L3MBTL1LMNANAPRTP4HTMCES2 | |
| 2-Picolinic Acid SCHEMBL29480469 | 0.87 | LMNA (0.95) | L3MBTL1LMNANAPRTP4HTMCES2 | |
| 2-Picolinic Acid SCHEMBL134791 | 0.87 | LMNA (0.95) | L3MBTL1LMNANAPRTP4HTMCES2 | |
| 2-Picolinic Acid SCHEMBL29360523 | 0.87 | LMNA (0.95) | L3MBTL1LMNANAPRTP4HTMCES2 | |
| 2-Picolinic Acid SCHEMBL664133 | 0.87 | LMNA (0.95) | L3MBTL1LMNANAPRTP4HTMCES2 | |
| 2-Picolinic Acid SCHEMBL674979 | 0.87 | LMNA (0.95) | L3MBTL1LMNANAPRTP4HTMCES2 | |
| 2-Picolinic Acid SCHEMBL1462616 | 0.87 | LMNA (0.95) | L3MBTL1LMNANAPRTP4HTMCES2 | |
| 2-Picolinic Acid SCHEMBL673571 | 0.87 | LMNA (0.95) | L3MBTL1LMNANAPRTP4HTMCES2 | |
| 2-Picolinic Acid SCHEMBL28174521 | 0.85 | LMNA (0.91) | L3MBTL1LMNANAPRTP4HTMCES2 | |
| 2-Picolinic Acid SCHEMBL27695178 | 0.85 | LMNA (0.91) | L3MBTL1LMNANAPRTP4HTMCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288424-B2 | Substituted tetrahydroimidazopyridine compounds and the use thereof in the treatment of pain and other conditions | GRUENENTHAL GMBH (DE) | 2012-10-16 | — | — | US | claimed |
| EP-2235013-B1 | SUBSTITUTED TETRAHYDROIMIDAZOPYRIDINE COMPOUNDS AND THE USE THEREOF IN PHARMACEUTICALS | GRUENENTHAL GMBH (DE) | 2012-08-01 | — | — | EP | claimed |
| US-20090186902-A1 | Substituted Tetrahydroimidazopyridine Compounds and the Use Thereof in the Treatment of Pain and Other Conditions | GRUENENTHAL GMBH (DE) | 2009-07-23 | — | — | US | claimed |
| EP-0812185-B1 | USE OF ANGIOGENESIS SUPPRESSORS FOR INHIBITING HAIR GROWTH | GILLETTE CO (US) | 2002-07-03 | — | — | EP | claimed |
| US-6093748-A | APPLYING TO AN AREA OF SKIN FROM WHICH REDUCED HAIR GROWTH IS DESIRED A DERMATOLOGICALLY ACCEPTABLE COMPOSITION CONTAINING A NON-STEROIDAL SUPPRESSOR OF ANGIOGENESIS | AHLUWALIA GURPREET S (US) | 2000-07-25 | — | — | US | claimed |
| EP-0812185-A2 | USE OF ANGIOGENESIS SUPPRESSORS FOR INHIBITING HAIR GROWTH | HANDELMAN, Joseph H. (US) | 1997-12-17 | — | — | EP | claimed |
| WO-1996026712-A2 | USE OF ANGIOGENESIS SUPPRESSORS FOR INHIBITING HAIR GROWTH | HANDELMAN, JOSEPH, H. (US) | 1996-09-06 | — | — | WO | claimed |
| EP-0812185-B1 | USE OF ANGIOGENESIS SUPPRESSORS FOR INHIBITING HAIR GROWTH | GILLETTE CO (US) | 2002-07-03 | — | — | EP | disclosed |
| US-6093748-A | APPLYING TO AN AREA OF SKIN FROM WHICH REDUCED HAIR GROWTH IS DESIRED A DERMATOLOGICALLY ACCEPTABLE COMPOSITION CONTAINING A NON-STEROIDAL SUPPRESSOR OF ANGIOGENESIS | AHLUWALIA GURPREET S (US) | 2000-07-25 | — | — | US | disclosed |
| EP-0812185-A2 | USE OF ANGIOGENESIS SUPPRESSORS FOR INHIBITING HAIR GROWTH | HANDELMAN, Joseph H. (US) | 1997-12-17 | — | — | EP | disclosed |
| WO-1996026712-A2 | USE OF ANGIOGENESIS SUPPRESSORS FOR INHIBITING HAIR GROWTH | HANDELMAN, JOSEPH, H. (US) | 1996-09-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090186902-A1 | Substituted Tetrahydroimidazopyridine Compounds and the Use Thereof in the Treatment of Pain and Other Conditions | HRH4, TRPV1, QDPR | L3MBTL1 3734/4885LMNA 1246/4885NAPRT 3116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.