2-Picolinic Acid

2-Picolinic Acid

SCHEMBL674979

O=C(O)c1ccccn1.O=C(O)c1ccccn1.[Cr]

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.95
L3MBTL1 Q9Y468 2/20 0.95
NAPRT Q6XQN6 1/20 0.95
P4HTM Q9NXG6 1/20 0.95
CES2 O00748 1/20 0.67
CES1 P23141 1/20 0.67
KMT2A Q03164 2/20 0.63
ALDH1A1 P00352 2/20 0.61
GSK3B P49841 1/20 0.55
KDM4E B2RXH2 4/20 0.53
NPC1 O15118 3/20 0.53
RAB9A P51151 3/20 0.53
MAPT P10636 2/20 0.53
PKM P14618 2/20 0.53
TDP1 Q9NUW8 2/20 0.52
ALOX15 P16050 1/20 0.52
TSHR P16473 1/20 0.52
ACMSD Q8TDX5 1/20 0.52
PTGS2 P35354 1/20 0.50
CTNNB1 P35222 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Picolinic Acid SCHEMBL134791 1.00 LMNA (0.95) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL1462616 1.00 LMNA (0.95) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL664133 1.00 LMNA (0.95) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL29480469 1.00 LMNA (0.95) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL29360523 1.00 LMNA (0.95) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL27680667 0.98 LMNA (0.91) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL28174521 0.98 LMNA (0.91) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL6285136 0.98 LMNA (0.91) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL27695178 0.98 LMNA (0.91) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL674837 0.98 LMNA (1.00) LMNAL3MBTL1NAPRTP4HTMCES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240148748-A1 CHROMIUM CONTAINING COMPOSITIONS FOR IMPROVING HEALTH AND FITNESS NUTRITION21 LLC (US) 2024-05-09 US disclosed
US-11865121-B2 Chromium containing compositions for improving health and fitness Nutrition21, LLC (US) 2024-01-09 US disclosed
US-11857553-B2 Chromium containing compositions for improving health and fitness Nutrition21, LLC (US) 2024-01-02 US disclosed
EP-3050568-B1 METHODS AND COMPOSITIONS FOR THE SUSTAINED RELEASE OF CHROMIUM JDS THERAPEUTICS LLC (US) 2020-12-02 EP disclosed
US-20190314510-A1 METHODS AND COMPOSITIONS FOR THE SUSTAINED RELEASE OF CHROMIUM CAPITAL ONE, NATIONAL ASSOCIATION, AS AGENT 2019-10-17 US disclosed
US-20190216821-A1 Chromium Containing Compositions for Improving Health and Fitness CAPITAL ONE, NATIONAL ASSOCIATION, AS AGENT 2019-07-18 US disclosed
US-10245325-B2 Methods and compositions for the sustained release of chromium JDS THERAPEUTICS, LLC (US) 2019-04-02 US disclosed
EP-3413900-A1 CHROMIUM CONTAINING COMPOSITIONS FOR IMPROVING HEALTH AND FITNESS Nutrition 21, LLC (US) 2018-12-19 EP disclosed
US-20170304360-A1 METHODS AND COMPOSITIONS FOR THE SUSTAINED RELEASE OF CHROMIUM CAPITAL ONE, NATIONAL ASSOCIATION, AS AGENT 2017-10-26 US disclosed
US-20170239267-A1 CHROMIUM CONTAINING COMPOSITIONS FOR IMPROVING HEALTH AND FITNESS CAPITAL ONE, NATIONAL ASSOCIATION, AS AGENT 2017-08-24 US disclosed
EP-3050568-A1 METHODS AND COMPOSITIONS FOR THE SUSTAINED RELEASE OF CHROMIUM Nutrition 21, Inc. (US) 2016-08-03 EP disclosed
EP-2134351-B1 METHODS AND COMPOSITIONS FOR THE SUSTAINED RELEASE OF CHROMIUM NUTRITION 21 INC (US) 2016-04-27 EP disclosed
US-20150320874-A1 METHODS AND COMPOSITIONS FOR THE SUSTAINED RELEASE OF CHROMIUM CAPITAL ONE, NATIONAL ASSOCIATION, AS AGENT 2015-11-12 US disclosed
US-20150320796-A1 METHODS AND COMPOSITIONS FOR THE SUSTAINED RELEASE OF CHROMIUM CAPITAL ONE, NATIONAL ASSOCIATION, AS AGENT 2015-11-12 US disclosed
US-9119835-B2 Methods and compositions for the sustained release of chromium JDS Therapeautics, LLC (US) 2015-09-01 US disclosed
US-20120128794-A1 METHODS AND COMPOSITIONS FOR THE SUSTAINED RELEASE OF CHROMIUM NUTRITION 21, INC. (US) 2012-05-24 US disclosed
US-8062677-B2 Methods and compositions for the sustained release of chromium NUTRITION 21, INC. (US) 2011-11-22 US disclosed
EP-2134351-A1 METHODS AND COMPOSITIONS FOR THE SUSTAINED RELEASE OF CHROMIUM Nutrition 21, Inc. (US) 2009-12-23 EP disclosed
US-20090155384-A1 METHODS AND COMPOSITIONS FOR THE SUSTAINED RELEASE OF CHROMIUM CAPITAL ONE, NATIONAL ASSOCIATION, AS AGENT 2009-06-18 US disclosed
WO-2008112706-A1 METHODS AND COMPOSITIONS FOR THE SUSTAINED RELEASE OF CHROMIUM NUTRITION 21, INC. (US) 2008-09-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090155384-A1 METHODS AND COMPOSITIONS FOR THE SUSTAINED RELEASE OF CHROMIUM LDLR, TNNC1, LIPA LMNA 229/4885L3MBTL1 4113/4885NAPRT 3844/4885
US-20120128794-A1 METHODS AND COMPOSITIONS FOR THE SUSTAINED RELEASE OF CHROMIUM LDLR, TNNC1, LIPA LMNA 229/4885L3MBTL1 4113/4885NAPRT 3844/4885
US-20150320874-A1 METHODS AND COMPOSITIONS FOR THE SUSTAINED RELEASE OF CHROMIUM LDLR, TNNC1, LIPA LMNA 229/4885L3MBTL1 4113/4885NAPRT 3844/4885
US-20190216821-A1 Chromium Containing Compositions for Improving Health and Fitness GYS1, MUSK, PYGM LMNA 1223/4885L3MBTL1 3744/4885NAPRT 4176/4885
US-20240148748-A1 CHROMIUM CONTAINING COMPOSITIONS FOR IMPROVING HEALTH AND FITNESS GYS1, MUSK, PYGM LMNA 1223/4885L3MBTL1 3744/4885NAPRT 4176/4885
US-20190314510-A1 METHODS AND COMPOSITIONS FOR THE SUSTAINED RELEASE OF CHROMIUM LDLR, TNNC1, LIPA LMNA 229/4885L3MBTL1 4113/4885NAPRT 3844/4885
US-11865121-B2 Chromium containing compositions for improving health and fitness GYS1, MUSK, PYGM LMNA 1223/4885L3MBTL1 3744/4885NAPRT 4176/4885
US-10245325-B2 Methods and compositions for the sustained release of chromium LDLR, TNNC1, LIPA LMNA 229/4885L3MBTL1 4113/4885NAPRT 3844/4885
US-20170239267-A1 CHROMIUM CONTAINING COMPOSITIONS FOR IMPROVING HEALTH AND FITNESS GYS1, MUSK, PYGM LMNA 1223/4885L3MBTL1 3744/4885NAPRT 4176/4885
US-20170304360-A1 METHODS AND COMPOSITIONS FOR THE SUSTAINED RELEASE OF CHROMIUM LDLR, TNNC1, LIPA LMNA 229/4885L3MBTL1 4113/4885NAPRT 3844/4885
US-11857553-B2 Chromium containing compositions for improving health and fitness GYS1, MUSK, PYGM LMNA 1223/4885L3MBTL1 3744/4885NAPRT 4176/4885
US-20150320796-A1 METHODS AND COMPOSITIONS FOR THE SUSTAINED RELEASE OF CHROMIUM LDLR, TNNC1, LIPA LMNA 229/4885L3MBTL1 4113/4885NAPRT 3844/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.