SCHEMBL4089174

SCHEMBL4089174

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nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TERT O14746 1/20 0.31
CTSC P53634 1/20 0.30
PSMB5 P28074 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18116800 0.80 TERT (0.36) TERTCTSCPSMB5
SCHEMBL16620266 0.79 DPP4 (0.39) TERT
SCHEMBL19331517 0.79 TERT (0.40) TERTPSMB5
SCHEMBL19331515 0.79 TERT (0.40) TERTPSMB5
SCHEMBL4087867 0.78 TERT (0.32) TERTCTSCPSMB5
SCHEMBL4092811 0.78 CTSC (0.32) CTSC
SCHEMBL30869183 0.72 METAP1 (0.38) TERTCTSC
SCHEMBL29421862 0.72 NPSR1 (0.39)
SCHEMBL31461744 0.71 ECE1 (0.48) CTSC
SCHEMBL4087334 0.71 CTSC (0.33) CTSC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8076285-B2 Lysobactin amides AICURIS GMBH & CO. KG (DE) 2011-12-13 US disclosed
US-20090203582-A1 LYSOBACTIN AMIDES BAYER HEALTHCARE AG (DE) 2009-08-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090203582-A1 LYSOBACTIN AMIDES AADAT, HAMP, DLST TERT 3633/4885CTSC 619/4885PSMB5 2523/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.