Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.57 |
| ▸ | SCD5 | Q86SK9 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.53 |
| ▸ | SCD | O00767 | 2/20 | 0.53 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11903396 | 0.93 | ALDH1A1 (0.64) | ALDH1A1PTPN1SCD5MAPTHPGD | |
| SCHEMBL12243261 | 0.83 | S1PR1 (0.56) | SCD5S1PR1SCDS1PR3NPC1 | |
| SCHEMBL4020118 | 0.78 | ALDH1A1 (0.60) | ALDH1A1PTPN1SCD5MAPTHPGD | |
| SCHEMBL12243237 | 0.77 | S1PR1 (0.50) | ALDH1A1SCD5MAPTS1PR1SCD | |
| SCHEMBL72786 | 0.75 | ALDH1A1 (1.00) | ALDH1A1PTPN1MAPTHPGDRECQL | |
| SCHEMBL2353237 | 0.75 | S1PR1 (0.48) | ALDH1A1SCD5MAPTS1PR1SCD | |
| SCHEMBL71299 | 0.74 | ALDH1A1 (1.00) | ALDH1A1PTPN1MAPTHPGDRECQL | |
| SCHEMBL891863 | 0.73 | S1PR3 (0.65) | ALDH1A1MAPTS1PR1S1PR3KMT2A | |
| SCHEMBL1178695 | 0.73 | ALDH1A1 (0.72) | ALDH1A1PTPN1MAPTHPGDRECQL | |
| SCHEMBL892967 | 0.73 | CDH1 (0.82) | ALDH1A1PTPN1MAPTHPGDRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069288-A1 | Novel therapeutic compounds | ABBVIE INC. | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069288-A1 | Novel therapeutic compounds | MAP3K20, RPS6KB1, MAP3K1 | ALDH1A1 1426/4885PTPN1 2039/4885SCD5 3893/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.