Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.44 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | NEK2 | P51955 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3559657 | 0.79 | ALDH1A1 (0.54) | BCAT2BTKARKDM4EALDH1A1 | |
| SCHEMBL28522305 | 0.78 | MYC (0.56) | MYCBCAT2CHEK1KDM4EALDH1A1 | |
| SCHEMBL4138458 | 0.76 | MYC (0.72) | MYCBCAT2KDM4EALDH1A1GAA | |
| SCHEMBL3467227 | 0.76 | BTK (0.51) | BTKNEK2CHEK1CHEK2HDAC1 | |
| SCHEMBL2417966 | 0.75 | PKM (0.43) | MYCBTKARKDM4EALDH1A1 | |
| SCHEMBL30207687 | 0.74 | MYC (0.51) | MYCBCAT2KDM4EALDH1A1MAPT | |
| SCHEMBL2417969 | 0.74 | ALDH1A1 (0.49) | BCAT2BTKNEK2ARKDM4E | |
| SCHEMBL3756657 | 0.70 | PTPN1 (0.50) | FTOHDAC1HDAC2KDM4EALDH1A1 | |
| SCHEMBL27758304 | 0.70 | BCAT2 (0.59) | MYCBCAT2CHEK1KDM4EALDH1A1 | |
| SCHEMBL28057673 | 0.70 | MYC (0.46) | MYCBCAT2KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009103778-A1 | COMPOUNDS AND METHODS | NOVASAID AB (SE) | 2009-08-27 | — | — | WO | disclosed |