Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 5/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4086117 | 0.79 | HSD17B1 (0.50) | MAPTMEN1GAAKMT2AALDH1A1 | |
| SCHEMBL4092430 | 0.78 | NR1H4 (0.61) | MAPTMEN1GAAKMT2AALDH1A1 | |
| SCHEMBL21775723 | 0.73 | ALPL (0.58) | MAPTALDH1A1ALPLCA9CA12 | |
| SCHEMBL4097796 | 0.71 | ALPL (0.64) | MAPTMEN1GAAKMT2AALDH1A1 | |
| SCHEMBL20575703 | 0.70 | PDE4A (0.60) | MAPTMEN1GAAKMT2AALDH1A1 | |
| SCHEMBL167088 | 0.70 | MAPT (0.67) | MAPTMEN1GAAKMT2AALDH1A1 | |
| SCHEMBL4858146 | 0.69 | ALDH1A1 (0.62) | MAPTGAAALDH1A1ALPLRAB9A | |
| SCHEMBL4092658 | 0.69 | HSD17B1 (0.45) | MAPTMEN1GAAKMT2AALDH1A1 | |
| SCHEMBL4566709 | 0.69 | NR1H4 (0.37) | MEN1KMT2ALMNAMAPK1 | |
| SCHEMBL27785802 | 0.68 | HRH3 (0.46) | MAPTALPLCA9CA12RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090186900-A1 | COMPOUND | STERIX LIMITED (GB) | 2009-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090186900-A1 | COMPOUND | HSD17B2, HSD17B11, CYP17A1 | MAPT 929/4885MEN1 1122/4885GAA 316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.