Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | TYK2 | P29597 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | SMO | Q99835 | 2/20 | 0.43 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4096059 | 0.99 | RAB9A (0.49) | RAB9ASMN1; SMN2LMNATP53GAA | |
| SCHEMBL1473951 | 0.87 | NPC1 (0.54) | RAB9ASMN1; SMN2LMNATP53GAA | |
| Hydrochloric Acid SCHEMBL1471256 | 0.86 | NPC1 (0.53) | RAB9ASMN1; SMN2LMNATP53GAA | |
| SCHEMBL244941 | 0.86 | PTPN11 (0.46) | RAB9ASMN1; SMN2GAANPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL247568 | 0.85 | PTPN11 (0.45) | RAB9ASMN1; SMN2GAANPC1ALDH1A1 | |
| SCHEMBL4095632 | 0.85 | KMT2A (0.53) | RAB9ASMN1; SMN2LMNATP53GAA | |
| SCHEMBL2063619 | 0.85 | ALKBH1 (0.50) | RAB9AKMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL4089952 | 0.84 | KMT2A (0.52) | RAB9ASMN1; SMN2LMNATP53GAA | |
| Hydrochloric Acid SCHEMBL2063475 | 0.84 | ALKBH1 (0.49) | RAB9AKMT2ANPC1 | |
| SCHEMBL1150146 | 0.83 | CRACR2A (0.47) | RAB9ALMNATP53NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090197872-A1 | NOVEL 1,4-DIAZA-BICYCLO[3.2.2]NONYL PYRIMIDINYL DERIVATIVES AND THEIR MEDICAL USE | NEUROSEARCH A/S (DK) | 2009-08-06 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090197872-A1 | NOVEL 1,4-DIAZA-BICYCLO[3.2.2]NONYL PYRIMIDINYL DERIVATIVES AND THEIR MEDICAL USE | CHRNA2, CHRNA6, CHRNA3 | RAB9A 2092/4885SMN1; SMN2 279/4885LMNA 2570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.