Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5058134 | 0.90 | CYP2A6 (0.48) | GPR52MAPTTDP1CYP2A6NPC1 | |
| SCHEMBL1115608 | 0.85 | MAOB (0.46) | GPR52TDP1CYP2A6SMN1; SMN2 | |
| SCHEMBL1987774 | 0.83 | MAOB (0.46) | LMNAMAPTNPSR1TDP1L3MBTL1 | |
| SCHEMBL8709601 | 0.82 | GPR52 (0.49) | GPR52TDP1CYP2A6SMN1; SMN2 | |
| SCHEMBL31197196 | 0.81 | GPR52 (0.55) | GPR52LMNAMAPTTDP1L3MBTL1 | |
| SCHEMBL3822095 | 0.81 | GPR52 (0.51) | GPR52MAPTTDP1NPC1RAB9A | |
| SCHEMBL1355705 | 0.80 | TAAR1 (0.56) | MAPT | |
| SCHEMBL7814468 | 0.80 | NFE2L2 (0.48) | GPR52LMNAMAPTL3MBTL1NPC1 | |
| SCHEMBL5632468 | 0.79 | GPR52 (0.54) | GPR52LMNATDP1L3MBTL1CYP2A6 | |
| SCHEMBL4608345 | 0.79 | GRIN2D (0.43) | LMNACYP2A6KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7482410-B2 | Processes for producing high density polyethylene | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2009-01-27 | — | — | US | disclosed |