Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 5/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 2/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9149351 | 0.84 | MLYCD (0.39) | ALDH1A1HPGDMEN1KMT2ALMNA | |
| SCHEMBL1857408 | 0.79 | SMN1; SMN2 (0.46) | GAAPKMCSF1RNTRK1KIT | |
| SCHEMBL8986703 | 0.77 | CCNC (0.43) | ALDH1A1KMT2AL3MBTL1PKMCSF1R | |
| SCHEMBL1075092 | 0.77 | CSF1R (0.41) | ALDH1A1CSF1RNTRK1KITAXL | |
| SCHEMBL276286 | 0.75 | ALDH1A1 (0.60) | ALDH1A1HPGDMEN1KMT2AL3MBTL1 | |
| SCHEMBL14393872 | 0.74 | KMT2A (0.58) | ALDH1A1HPGDMEN1KMT2AL3MBTL1 | |
| SCHEMBL1518124 | 0.73 | ALDH1A1 (0.53) | ALDH1A1HPGDMEN1KMT2AL3MBTL1 | |
| SCHEMBL2513855 | 0.73 | ALDH1A1 (0.51) | ALDH1A1HPGDMEN1KMT2AL3MBTL1 | |
| SCHEMBL13505930 | 0.73 | ALDH1A1 (0.51) | ALDH1A1HPGDMEN1KMT2AL3MBTL1 | |
| SCHEMBL3766521 | 0.73 | BAZ2B (0.50) | ALDH1A1MEN1KMT2ALMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260062443-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMA INC (US) | 2026-03-05 | — | — | US | disclosed |
| WO-2024044098-A2 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-29 | — | — | WO | disclosed |
| US-20160297830-A1 | NOVEL COMPOUNDS USEFUL FOR THE TREATMENT OF BACTERIAL INFECTIOUS DISEASES | GALAPAGOS NV (BE) | 2016-10-13 | — | — | US | disclosed |
| US-20090203737-A1 | Pyrrole Derivatives as Positive Allosteric Modulators of Metabotropic Receptors | ADDEX PHARMA SA (CH) | 2009-08-13 | — | — | US | disclosed |
| EP-1912979-A2 | PHENYL-3-{(3-(1H-PYRROL-2-YL)-[1,2,4]OXADIAZOL-5-YL]PIPERIDIN-1-YL}-METHANONE DERIVATIVES AND RELATED COMPOUNDS AS POSITIVE ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | ADDEX Pharma S.A. (CH) | 2008-04-23 | — | — | EP | disclosed |
| WO-2006123257-A2 | PHENYL-3-{(3-(1H-PYRROL-2-YL)-[1, 2 , 4]0XADIAZ0L-5-YL]PIPERIDIN-1-YL}-METHANONE DERIVATIVES AND RELATED COMPOUNDS AS POSITIVE ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | ADDEX PHARMA SA (CH) | 2006-11-23 | — | — | WO | disclosed |
| EP-0596204-B1 | Pyrrole thiocarboxamide insecticidal and acaricidal agents | AMERICAN CYANAMID CO (US) | 1996-06-26 | — | — | EP | disclosed |
| US-5389669-A | Inhibiting the insect growth by applying a pesticides | AMERICAN CYANAMID COMPANY (US) | 1995-02-14 | — | — | US | disclosed |
| EP-0431305-B1 | Process for the preparation of molluscicidal 2,4,5-tribromopyrrole-3-carbonitrile compounds | AMERICAN CYANAMID CO (US) | 1995-01-25 | — | — | EP | disclosed |
| EP-0596204-A1 | Pyrrole thiocarboxamide insecticidal and acaricidal agents | AMERICAN CYANAMID COMPANY (US) | 1994-05-11 | — | — | EP | disclosed |
| US-5286742-A | Agriculture | AMERICAN CYANAMID COMPANY (US) | 1994-02-15 | — | — | US | disclosed |
| EP-0431305-A1 | Process for the preparation of molluscicidal 2,4,5-tribromopyrrole-3-carbonitrile compounds | AMERICAN CYANAMID COMPANY (US) | 1991-06-12 | — | — | EP | disclosed |
| US-5008403-A | Deacylative bromination process for the preparation of molluscicidal 2,4,5-tribromopyrrole-3-carbonitrile compounds | AMERICAN CYANAMID COMPANY (US) | 1991-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260062443-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | C9, SSB, C1S | ALDH1A1 3835/4885HPGD 4023/4885MEN1 498/4885 |
| US-20160297830-A1 | NOVEL COMPOUNDS USEFUL FOR THE TREATMENT OF BACTERIAL INFECTIOUS DISEASES | POLR2E, POLB, POLI | ALDH1A1 2389/4885HPGD 1539/4885MEN1 3737/4885 |
| US-20090203737-A1 | Pyrrole Derivatives as Positive Allosteric Modulators of Metabotropic Receptors | GRM5, GRIK5, GRM2 | ALDH1A1 4261/4885HPGD 2812/4885MEN1 4289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.