Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 7/20 | 0.59 |
| ▸ | PTGES | O14684 | 2/20 | 0.46 |
| ▸ | CCR9 | P51686 | 2/20 | 0.42 |
| ▸ | EDNRB | P24530 | 4/20 | 0.42 |
| ▸ | EDNRA | P25101 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2810671 | 0.86 | SERPINE1 (0.59) | SERPINE1EDNRBEDNRAPPARG | |
| SCHEMBL5738857 | 0.85 | SERPINE1 (0.56) | SERPINE1PTGESCCR9EDNRBEDNRA | |
| SCHEMBL5812761 | 0.85 | PTGES (0.65) | SERPINE1PTGESEDNRBEDNRAPPARG | |
| SCHEMBL6093339 | 0.82 | SERPINE1 (0.61) | SERPINE1PTGESEDNRBEDNRAMEN1 | |
| SCHEMBL6091652 | 0.78 | SERPINE1 (0.54) | SERPINE1PTGESCCR9PPARGPTGES2 | |
| SCHEMBL4092414 | 0.78 | PTGES (0.72) | SERPINE1PTGESCCR9EDNRBEDNRA | |
| SCHEMBL6092174 | 0.77 | THRB (0.44) | SERPINE1PTGESMEN1CYP3A4MAPT | |
| SCHEMBL6091490 | 0.76 | TP53 (0.47) | PTGESEDNRBEDNRAMEN1KMT2A | |
| SCHEMBL2807015 | 0.76 | SERPINE1 (0.62) | SERPINE1PTGESEDNRBEDNRAPPARG | |
| SCHEMBL2810203 | 0.76 | SERPINE1 (0.62) | SERPINE1EDNRBEDNRAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060160879-A1 | Indoles useful in the treatment of inflammation | BIOLIPOX AB (SE) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160879-A1 | Indoles useful in the treatment of inflammation | IDO1, PTGS1, IDO2 | SERPINE1 508/4885PTGES 4/4885CCR9 1123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.