Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.52 |
| ▸ | CCR2 | P41597 | 3/20 | 0.42 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PKLR | P30613 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4086709 | 0.89 | PTGES (0.47) | PTGESPTGDR2PLA2G2AKDM4ELMNA | |
| SCHEMBL4086716 | 0.81 | PTGES (0.50) | PTGESCCR2ERCC5PLA2G2AKDM4E | |
| SCHEMBL4092463 | 0.79 | CCR2 (0.55) | PTGESCCR2MAPTTP53 | |
| SCHEMBL4093394 | 0.75 | CCR2 (0.55) | CCR2PTGDR2PDE1BKDM4ELMNA | |
| SCHEMBL4098784 | 0.72 | TP53 (0.46) | PTGESPLA2G2AKDM4ELMNAHPGD | |
| SCHEMBL4092414 | 0.72 | PTGES (0.72) | PTGESCCR2ERCC5PLA2G2AMAPT | |
| SCHEMBL4086022 | 0.69 | CCR2 (0.50) | CCR2PTGDR2PDE1BKDM4EMAPT | |
| SCHEMBL4093589 | 0.69 | PTGES (1.00) | PTGESCCR2ERCC5PPARG | |
| SCHEMBL4086498 | 0.67 | TP53 (0.46) | CCR2MAPTTP53POLB | |
| SCHEMBL18890618 | 0.67 | TP53 (0.58) | KDM4ELMNAHTTMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069384-A1 | THIENOPYRROLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069384-A1 | THIENOPYRROLES USEFUL IN THE TREATMENT OF INFLAMMATION | NPY5R, TH, PTGES | PTGES 3/4885CCR2 1118/4885ERCC5 3540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.