Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.62 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.57 |
| ▸ | NQO2 | P16083 | 1/20 | 0.57 |
| ▸ | CDK4 | P11802 | 1/20 | 0.49 |
| ▸ | CCND1 | P24385 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3235168 | 0.86 | TRPV1 (0.66) | MTNR1AMTNR1BTRPV1NQO2CDK4 | |
| SCHEMBL3767060 | 0.86 | CA2 (0.61) | MTNR1ANQO2KDM4EALDH1A1MEN1 | |
| SCHEMBL5437839 | 0.86 | MTNR1A (0.68) | MTNR1AMTNR1BTRPV1NQO2CDK4 | |
| SCHEMBL4408801 | 0.85 | MTNR1A (0.60) | MTNR1AMTNR1BTRPV1NQO2CDK4 | |
| SCHEMBL28317202 | 0.83 | HIF1A (0.63) | TRPV1KDM4EALDH1A1 | |
| SCHEMBL27382856 | 0.81 | MTNR1A (0.58) | MTNR1AMTNR1BTRPV1NQO2KDM4E | |
| SCHEMBL27382865 | 0.80 | MTNR1A (0.56) | MTNR1AMTNR1BTRPV1NQO2MEN1 | |
| SCHEMBL3237378 | 0.80 | MTNR1A (0.56) | MTNR1AMTNR1BTRPV1NQO2NPC1 | |
| SCHEMBL10630944 | 0.80 | ALDH1A1 (0.57) | KDM4EALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL7898025 | 0.77 | MTNR1A (0.68) | MTNR1AMTNR1BTRPV1NQO2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009103778-A1 | COMPOUNDS AND METHODS | NOVASAID AB (SE) | 2009-08-27 | — | — | WO | disclosed |