Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.51 |
| ▸ | CMA1 | P23946 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28698891 | 0.92 | KDM4E (0.67) | HTR2ATP53KDM4EHSD17B10HPGD | |
| SCHEMBL8493237 | 0.87 | HTR2A (0.63) | HTR2ATP53KDM4EHSD17B10HPGD | |
| SCHEMBL1326755 | 0.86 | CMA1 (0.63) | HTR2ATP53KDM4EHSD17B10HPGD | |
| SCHEMBL4573079 | 0.86 | HTR2A (0.61) | HTR2ATP53KDM4EHSD17B10HPGD | |
| SCHEMBL21766893 | 0.84 | HTR2A (0.64) | HTR2ATP53KDM4EHSD17B10HPGD | |
| SCHEMBL30958421 | 0.84 | ICMT (0.62) | HTR2AKDM4EKMT2AMEN1GPR84 | |
| SCHEMBL588980 | 0.84 | ICMT (0.62) | HTR2AKDM4EKMT2AMEN1GPR84 | |
| SCHEMBL1225107 | 0.84 | TP53 (0.65) | HTR2ATP53KDM4EHSD17B10HPGD | |
| Hydrochloric Acid SCHEMBL3155846 | 0.83 | ICMT (0.60) | HTR2AKDM4EKMT2AMEN1GPR84 | |
| SCHEMBL24247573 | 0.82 | TP53 (0.67) | HTR2ATP53KDM4EHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117969859-B | Metabolic biomarker for polycystic ovary syndrome and application thereof | 山东大学 | 2024-09-06 | — | — | CN | claimed |
| CN-117969859-A | Metabolic biomarker for polycystic ovary syndrome and application thereof | 山东大学 | 2024-05-03 | — | — | CN | claimed |
| US-5726319-A | Biphenyl substituted dipeptide analogs promote release of growth hormone | MERCK & CO., INC. (US) | 1998-03-10 | — | — | US | claimed |
| CN-117969859-B | Metabolic biomarker for polycystic ovary syndrome and application thereof | 山东大学 | 2024-09-06 | — | — | CN | disclosed |
| CN-117969859-A | Metabolic biomarker for polycystic ovary syndrome and application thereof | 山东大学 | 2024-05-03 | — | — | CN | disclosed |
| US-11149066-B2 | Thrombospondin 1-binding peptide | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2021-10-19 | — | — | US | disclosed |
| US-20200131230-A1 | THROMBOSPONDIN 1-BINDING PEPTIDE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2020-04-30 | — | — | US | disclosed |
| US-9206156-B2 | Substituted indole derivatives | Grünenthal GmbH (DE) | 2015-12-08 | — | — | US | disclosed |
| US-20130116283-A1 | Substituted indole derivatives | Grünenthal GmbH (DE) | 2013-05-09 | — | — | US | disclosed |
| US-20090215828-A1 | Substituted indole derivatives | GRUNENTHAL GMBH (DE) | 2009-08-27 | — | — | US | disclosed |
| US-5726319-A | Biphenyl substituted dipeptide analogs promote release of growth hormone | MERCK & CO., INC. (US) | 1998-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215828-A1 | Substituted indole derivatives | IDO1, IDO2, TPH1 | HTR2A 12/4885TP53 1464/4885KDM4E 2535/4885 |
| US-11149066-B2 | Thrombospondin 1-binding peptide | SERPINC1, TEK, ARGLU1 | HTR2A 4461/4885TP53 4241/4885KDM4E 4263/4885 |
| US-20200131230-A1 | THROMBOSPONDIN 1-BINDING PEPTIDE | SERPINC1, TEK, ARGLU1 | HTR2A 4461/4885TP53 4241/4885KDM4E 4263/4885 |
| US-20130116283-A1 | Substituted indole derivatives | IDO1, IDO2, TPH1 | HTR2A 12/4885TP53 1464/4885KDM4E 2535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.