Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2012936 | 0.70 | ALDH1A1 (0.46) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL4092944 | 0.69 | HTR2A (0.33) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL2082208 | 0.68 | CA12 (0.52) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL13885184 | 0.66 | JAK3 (0.42) | — | |
| SCHEMBL15724407 | 0.65 | KAT2B (0.41) | ALDH1A1CYP3A4CYP2D6MAPTCYP2C9 | |
| SCHEMBL4095742 | 0.63 | BRD4 (0.40) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL12405322 | 0.63 | KDM4E (0.39) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL12478214 | 0.62 | MAPT (0.41) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL31064183 | 0.62 | MAPT (0.41) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL23809344 | 0.61 | NOTUM (0.40) | CA1CA2KDM4EKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009055674-A1 | PYRROLOPYRIMIDINE ALKYNYL COMPOUNDS AND METHODS OF MAKING AND USING SAME | TARGEGEN INC. (US) | 2009-04-30 | — | — | WO | disclosed |