Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL4093963 | 0.94 | PAOX (0.53) | PAOXKDM4CKDM4APHF8KDM2A | |
| SCHEMBL19516596 | 0.82 | TDP1 (0.52) | PAOXKDM4CKDM4APHF8KDM2A | |
| Lactic Acid SCHEMBL8519748 | 0.81 | PAOX (0.54) | PAOXKDM4ETDP1ALDH1A1S1PR2 | |
| Hydrochloric Acid SCHEMBL31278439 | 0.80 | PAOX (0.50) | PAOXKDM4CKDM4APHF8KDM2A | |
| Lactic Acid SCHEMBL8518756 | 0.80 | PAOX (0.53) | PAOXKDM4ETDP1ALDH1A1S1PR2 | |
| Lactic Acid SCHEMBL29920920 | 0.78 | DNM1 (0.60) | PAOXKDM4CKDM4APHF8KDM2A | |
| Methyl Phosphonate SCHEMBL28378294 | 0.75 | S1PR2 (0.46) | KDM4CKDM4APHF8KDM2AANPEP | |
| SCHEMBL30463701 | 0.75 | CYP2C19 (0.50) | PAOXKDM4CKDM4APHF8KDM2A | |
| SCHEMBL30463700 | 0.75 | CYP2C19 (0.50) | PAOXKDM4CKDM4APHF8KDM2A | |
| SCHEMBL30463704 | 0.75 | CYP2C19 (0.50) | PAOXKDM4CKDM4APHF8KDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927019-A1 | COMPOSITIONS FOR COSMETIC APPLICATIONS | MedLogic Global Corporation (US) | 1999-07-07 | — | — | EP | disclosed |
| WO-1998048768-A1 | COMPOSITIONS FOR COSMETIC APPLICATIONS | MEDLOGIC GLOBAL CORPORATION (US) | 1998-11-05 | — | — | WO | disclosed |