Hydrochloric Acid

Hydrochloric Acid

SCHEMBL4094393

CC1=Cc2cc(-c3ccccc3)ccc2C1[Zr+2].[Cl-].[Cl-]

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.33
KDM1A O60341 2/20 0.33
KDM1B Q8NB78 1/20 0.33
NPC1 O15118 2/20 0.33
GAA P10253 2/20 0.33
KDM4E B2RXH2 2/20 0.33
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
ALOX5 P09917 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPK1 P28482 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CASP3 P42574 1/20 0.32
RAB9A P51151 1/20 0.32
SENP8 Q96LD8 1/20 0.32
SENP7 Q9BQF6 1/20 0.32
SENP6 Q9GZR1 1/20 0.32
TNKS2 Q9H2K2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7705066 0.87 GAA (0.33) KDM1ANPC1GAAKDM4EMEN1
Hydrochloric Acid SCHEMBL4059545 0.80 MAOA (0.33) MAOAKDM1AKDM1BNPC1GAA
Hydrochloric Acid SCHEMBL4092756 0.80 MAOA (0.33) MAOAKDM1AKDM1BNPC1GAA
SCHEMBL29049893 0.79 MAOA (0.35) MAOAKDM1AKDM1BGAAKDM4E
Hydrochloric Acid SCHEMBL18112870 0.79 ESR1 (0.33) MAOAKDM1AKDM1BNPC1GAA
Hydrochloric Acid SCHEMBL27505811 0.79 MAOA (0.32) MAOAKDM1AKDM1BNPC1GAA
SCHEMBL27479178 0.78 MAOA (0.34) MAOAKDM1AKDM1BNPC1GAA
Hydrochloric Acid SCHEMBL28994366 0.77 ACHE (0.32) ALDH1A1MAPK1
SCHEMBL18114327 0.77 MAOA (0.33) MAOAKDM1AKDM1BNPC1GAA
Hydrochloric Acid SCHEMBL6910738 0.76 MAOA (0.31) MAOAKDM1AKDM1BNPC1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009104782-A1 ETHYLENE HOMOPOLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-08-27 WO disclosed
WO-2009104783-A1 CATALYST COMPONENT FOR POLYMERIZATION OF ETHYLENE AND PROCESS FOR PRODUCING ETHYLENE POLYMER (2) SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-08-27 WO disclosed
WO-2009104785-A1 CATALYST COMPONENT FOR POLYMERIZATION OF ETHYLENE AND PROCESS FOR PRODUCING ETHYLENE POLYMER (1) SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-08-27 WO disclosed