Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | HAO2 | Q9NYQ3 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.31 |
| ▸ | EDNRB | P24530 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4094393 | 0.80 | MAOA (0.33) | MAOAHAO2KDM1AKDM1BGAA | |
| Hydrochloric Acid SCHEMBL4059545 | 0.80 | MAOA (0.33) | MAOAKDM1AKDM1BGAAKDM4E | |
| SCHEMBL29049893 | 0.79 | MAOA (0.35) | MAOAKDM1AKDM1BGAAKDM4E | |
| Hydrochloric Acid SCHEMBL27505811 | 0.79 | MAOA (0.32) | MAOAKDM1AKDM1BGAAKDM4E | |
| Hydrochloric Acid SCHEMBL18112870 | 0.79 | ESR1 (0.33) | MAOAKDM1AKDM1BGAAKDM4E | |
| SCHEMBL27479178 | 0.78 | MAOA (0.34) | MAOAKDM1AKDM1BGAAMEN1 | |
| SCHEMBL18114327 | 0.77 | MAOA (0.33) | MAOAKDM1AKDM1BGAANPC1 | |
| Hydrochloric Acid SCHEMBL6910738 | 0.76 | MAOA (0.31) | MAOAKDM1AKDM1BGAAKDM4E | |
| Hydrochloric Acid SCHEMBL4089359 | 0.76 | CYP11B1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL5606827 | 0.75 | KDM4E (0.31) | MAOAKDM1AKDM1BKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110305605-B | Adhesive compositions made from propylene-based polymers and crystalline C2/C3 homopolymers | 埃克森美孚化学专利公司 | 2021-12-14 | — | — | CN | disclosed |
| CN-107109000-B | Heat activated fabrics made from blends containing propylene-based polymers | 埃克森美孚化学专利公司 | 2021-04-27 | — | — | CN | disclosed |
| CN-107429015-B | Propylene-based polymer compositions for handle applications | 埃克森美孚化学专利公司 | 2021-03-23 | — | — | CN | disclosed |
| CN-107406641-B | Propylene-based polymer composition for injection molding | 埃克森美孚化学专利公司 | 2021-03-16 | — | — | CN | disclosed |
| CN-106604960-B | Polymer compositions and nonwoven materials made therefrom | 埃克森美孚化学专利公司 | 2020-12-29 | — | — | CN | disclosed |
| CN-107567487-B | Adhesive composition made of propylene-based polymer for elastic connection | 埃克森美孚化学专利公司 | 2020-06-05 | — | — | CN | disclosed |
| WO-2009104782-A1 | ETHYLENE HOMOPOLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-08-27 | — | — | WO | disclosed |
| WO-2009104785-A1 | CATALYST COMPONENT FOR POLYMERIZATION OF ETHYLENE AND PROCESS FOR PRODUCING ETHYLENE POLYMER (1) | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-08-27 | — | — | WO | disclosed |
| CN-1152897-C | Propylene/ethylene-a-olefin block copolymer and process for producing the same | ס�ѻ�ѧ��ҵ��ʽ���� | 2004-06-09 | — | — | CN | disclosed |
| CN-1170008-A | Propylene/ethylene-a-olefin block copolymer and process for producing the same | SUMITOMO CHEMICAL CO (JP) | 1998-01-14 | — | — | CN | disclosed |