Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KYNU | Q16719 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 6/20 | 0.40 |
| ▸ | CTSS | P25774 | 5/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.38 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 5/20 | 0.38 |
| ▸ | CTSB | P07858 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4091635 | 0.83 | GSTP1 (0.47) | KYNUALDH1A1ALOX15SIRT2SIRT1 | |
| SCHEMBL13774903 | 0.79 | GRM8 (0.53) | KYNUALDH1A1ALOX15SIRT2SIRT1 | |
| SCHEMBL31405459 | 0.77 | KYNU (0.55) | KYNUALDH1A1ALOX15SIRT2SIRT1 | |
| SCHEMBL4089580 | 0.77 | GSTP1 (0.45) | KYNUALDH1A1ALOX15SIRT2SIRT1 | |
| SCHEMBL4103446 | 0.76 | KYNU (0.44) | KYNUALDH1A1ALOX15SIRT2SIRT1 | |
| SCHEMBL4084378 | 0.76 | CTSL (0.48) | KYNUALDH1A1ALOX15CTSLGSTP1 | |
| SCHEMBL4100004 | 0.76 | GSTP1 (0.48) | KYNUALDH1A1ALOX15SIRT2SIRT1 | |
| SCHEMBL4094926 | 0.75 | CTSL (0.44) | KYNUALDH1A1ALOX15SIRT2SIRT1 | |
| SCHEMBL11127646 | 0.74 | KYNU (0.56) | KYNUALDH1A1ALOX15SIRT2SIRT1 | |
| SCHEMBL2156000 | 0.74 | KYNU (0.58) | KYNUALDH1A1ALOX15SIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090170813-A1 | Hypophosphorous Acid Derivatives and their Therapeutical Applications | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2009-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170813-A1 | Hypophosphorous Acid Derivatives and their Therapeutical Applications | P4HA1, CYP2R1, EGLN3 | KYNU 2750/4885ALDH1A1 2089/4885ALOX15 1960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.