Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 8/20 | 0.65 |
| ▸ | CHEK1 | O14757 | 7/20 | 0.58 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3743125 | 0.83 | NPC1 (0.64) | CHEK1MAP4K4NPC1MAPTRAB9A | |
| SCHEMBL3812791 | 0.81 | ALDH1A1 (0.71) | ALOX15MAPTRAB9ANPSR1CNR2 | |
| SCHEMBL4080887 | 0.78 | ALOX15 (0.57) | ALOX15CHEK1CNR2 | |
| SCHEMBL3804151 | 0.78 | ALOX15 (0.57) | ALOX15CHEK1CNR2 | |
| SCHEMBL4096330 | 0.76 | CNR2 (0.48) | CNR2 | |
| SCHEMBL1564746 | 0.73 | CHEK1 (1.00) | ALOX15CHEK1MAP4K4 | |
| SCHEMBL1564586 | 0.73 | CHEK1 (1.00) | ALOX15CHEK1MAP4K4 | |
| SCHEMBL4086750 | 0.73 | CNR2 (0.53) | NPC1MAPTRAB9ACNR2 | |
| SCHEMBL1563875 | 0.72 | CHEK1 (1.00) | ALOX15CHEK1MAP4K4 | |
| SCHEMBL30286125 | 0.69 | ALOX15 (1.00) | ALOX15CHEK1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8338623-B2 | N-{3-[(2,5-dimethylmorpholin-4-yl)carbonyl]-4,7-dihydro-5H-thieno[2,3-c]pyran-2-yl}hexahydro-2,5-methanopentalene-3a(1H)-carboxamide; CB2 receptors ligand; antiinflammatory, analgesic agent; autoimmune diseases; neuroprotectants | ABBVIE INC. (US) | 2012-12-25 | — | — | US | disclosed |
| US-20090018114-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2009-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018114-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | CNR1, CNR2, GPR18 | ALOX15 1251/4885CHEK1 2624/4885MAP4K4 2010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.