Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4102274 | 0.94 | NLRP3 (0.33) | NR1H2NR1H3CRHR1P2RX7 | |
| SCHEMBL4091287 | 0.91 | METAP2 (0.32) | — | |
| SCHEMBL4090200 | 0.90 | GPBAR1 (0.34) | GPBAR1 | |
| SCHEMBL4106287 | 0.88 | SMN1; SMN2 (0.35) | GPBAR1CRHR1DHFR | |
| SCHEMBL4101972 | 0.87 | CRHR1 (0.33) | NR1H2NR1H3CRHR1DHFR | |
| SCHEMBL4091530 | 0.87 | MAP4K1 (0.38) | GPBAR1ROCK2ROCK1NR1H2NR1H3 | |
| SCHEMBL4107196 | 0.86 | RXFP1 (0.38) | GPBAR1NR1H2NR1H3CRHR1DHFR | |
| SCHEMBL4107183 | 0.86 | CRHR1 (0.35) | GPBAR1NR1H2NR1H3CRHR1DHFR | |
| SCHEMBL4101998 | 0.85 | HPGD (0.35) | NR1H2NR1H3CRHR1DHFR | |
| SCHEMBL4105401 | 0.85 | MAPT (0.34) | NR1H2NR1H3CRHR1DHFRMAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090234117-A1 | Pyrazolopyrimidine Derivative | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-09-17 | — | — | US | disclosed |
| EP-1903045-A1 | PYRAZOLOPYRIMIDINE DERIVATIVE | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-03-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090234117-A1 | Pyrazolopyrimidine Derivative | MC2R, CRHR1, AVPR2 | GPBAR1 291/4885ROCK2 3506/4885ROCK1 3539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.