Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 15/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | GPR183 | P32249 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3986348 | 0.83 | LIPE (0.44) | LIPEGPR119 | |
| SCHEMBL3986213 | 0.82 | PTGS1 (0.43) | LIPEGPR119PTGS2PTGS1GPR183 | |
| SCHEMBL387584 | 0.82 | GPR119 (0.60) | GPR119 | |
| SCHEMBL3986009 | 0.81 | LIPE (0.45) | LIPEGPR119PTGS2PTGS1 | |
| SCHEMBL2883378 | 0.80 | GPR119 (0.56) | GPR119 | |
| SCHEMBL15539741 | 0.80 | KCNH2 (0.43) | GPR119PTGS2PTGS1GPR183 | |
| SCHEMBL387864 | 0.80 | GPR119 (0.60) | GPR119 | |
| SCHEMBL15538841 | 0.80 | GPR119 (0.41) | GPR119PTGS2PTGS1GPR183 | |
| SCHEMBL3983168 | 0.79 | ALDH1A1 (0.45) | LIPEGPR119PTGS2PTGS1 | |
| SCHEMBL3988318 | 0.79 | ALDH1A1 (0.45) | GPR119PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2059516-A1 | PYRIDINE COMPOUNDS FOR TREATING GPR119 RELATED DISORDERS | BIOVITRUM AB (publ) (SE) | 2009-05-20 | — | — | EP | disclosed |
| WO-2008025798-A1 | PYRIDINE COMPOUNDS FOR TREATING GPR119 RELATED DISORDERS | BIOVITRUM AB (PUBL) (SE) | 2008-03-06 | — | — | WO | disclosed |