Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17072464 | 0.89 | SMN1; SMN2 (0.35) | ALDH1A1TRPA1SMN1; SMN2CYP1A2POLB | |
| SCHEMBL15743397 | 0.89 | SMN1; SMN2 (0.35) | ALDH1A1TRPA1SMN1; SMN2CYP1A2POLB | |
| SCHEMBL8232933 | 0.89 | CYP1A2 (0.43) | ALDH1A1TRPA1CYP1A2GAAALOX15 | |
| SCHEMBL28644708 | 0.77 | SMN1; SMN2 (0.38) | ALDH1A1TRPA1SMN1; SMN2CYP1A2POLB | |
| SCHEMBL710885 | 0.76 | PPARD (0.54) | ALDH1A1TRPA1SMN1; SMN2CYP1A2POLB | |
| SCHEMBL11025207 | 0.74 | CYP1A2 (0.44) | ALDH1A1TRPA1SMN1; SMN2CYP1A2POLB | |
| SCHEMBL7716763 | 0.74 | PPARD (0.55) | ALDH1A1TRPA1SMN1; SMN2CYP1A2POLB | |
| SCHEMBL11806061 | 0.73 | GAA (0.50) | ALDH1A1TRPA1SMN1; SMN2CYP1A2POLB | |
| SCHEMBL2354099 | 0.73 | CYP1A2 (0.42) | ALDH1A1TRPA1SMN1; SMN2CYP1A2POLB | |
| SCHEMBL8231853 | 0.72 | ALDH1A1 (0.44) | ALDH1A1TRPA1SMN1; SMN2CYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3122757-B1 | CHARGED LINKERS AND THEIR USES FOR CONJUGATION | HANGZHOU DAC BIOTECH CO LTD (CN) | 2023-09-06 | — | — | EP | disclosed |
| US-10696700-B2 | Charged linkers and their uses for conjugation | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2020-06-30 | — | — | US | disclosed |
| US-10696699-B2 | Charged linkers and their uses for conjugation | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2020-06-30 | — | — | US | disclosed |
| US-10683314-B2 | Charged linkers and their uses for conjugation | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2020-06-16 | — | — | US | disclosed |
| US-20190127401-A1 | CHARGED LINKERS AND THEIR USES FOR CONJUGATION | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2019-05-02 | — | — | US | disclosed |
| US-20190127399-A1 | CHARGED LINKERS AND THEIR USES FOR CONJUGATION | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2019-05-02 | — | — | US | disclosed |
| US-20190127400-A1 | CHARGED LINKERS AND THEIR USES FOR CONJUGATION | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2019-05-02 | — | — | US | disclosed |
| US-10131682-B2 | Hydrophilic linkers and their uses for conjugation of drugs to a cell binding molecules | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2018-11-20 | — | — | US | disclosed |
| EP-2922818-B1 | HYDROPHILIC LINKERS AND THEIR USES FOR CONJUGATION OF DRUGS TO CELL BINDING MOLECULES | HANGZHOU DAC BIOTECH CO LTD (CN) | 2018-09-05 | — | — | EP | disclosed |
| US-20170152274-A1 | CHARGED LINKERS AND THEIR USES FOR CONJUGATION | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2017-06-01 | — | — | US | disclosed |
| US-20150250896-A1 | HYDROPHILIC LINKERS AND THEIR USES FOR CONJUGATION OF DRUGS TO A CELL BINDING MOLECULES | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2015-09-10 | — | — | US | disclosed |
| US-20150250896-A1 | HYDROPHILIC LINKERS AND THEIR USES FOR CONJUGATION OF DRUGS TO A CELL BINDING MOLECULES | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2015-09-10 | — | — | US | disclosed |
| US-20150250896-A1 | HYDROPHILIC LINKERS AND THEIR USES FOR CONJUGATION OF DRUGS TO A CELL BINDING MOLECULES | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2015-09-10 | — | — | US | disclosed |
| WO-2014080251-A1 | HYDROPHILIC LINKERS AND THEIR USES FOR CONJUGATION OF DRUGS TO CELL BINDING MOLECULES | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2014-05-30 | — | — | WO | disclosed |
| US-20090170813-A1 | Hypophosphorous Acid Derivatives and their Therapeutical Applications | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2009-07-02 | — | — | US | disclosed |
| US-20090170813-A1 | Hypophosphorous Acid Derivatives and their Therapeutical Applications | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2009-07-02 | — | — | US | disclosed |
| US-20090170813-A1 | Hypophosphorous Acid Derivatives and their Therapeutical Applications | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2009-07-02 | — | — | US | disclosed |
| EP-1937699-A2 | HYPOPHOSPHOROUS ACID DERIVATIVES AND THEIR THERAPEUTICAL APPLICATIONS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007052169-A2 | HYPOPHOSPHOROUS ACID DERIVATIVES AND THEIR THERAPEUTICAL APPLICATIONS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2007-05-10 | — | — | WO | disclosed |
| WO-2007052169-A2 | HYPOPHOSPHOROUS ACID DERIVATIVES AND THEIR THERAPEUTICAL APPLICATIONS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2007-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170152274-A1 | CHARGED LINKERS AND THEIR USES FOR CONJUGATION | PHOSPHO1, PCTP, CD2BP2 | ALDH1A1 4122/4885TRPA1 4872/4885SMN1; SMN2 3710/4885 |
| US-20190127399-A1 | CHARGED LINKERS AND THEIR USES FOR CONJUGATION | PHOSPHO1, PCTP, CD2BP2 | ALDH1A1 4122/4885TRPA1 4872/4885SMN1; SMN2 3710/4885 |
| US-10131682-B2 | Hydrophilic linkers and their uses for conjugation of drugs to a cell binding molecules | CD44, EPCAM, ABCG2 | ALDH1A1 1784/4885TRPA1 4847/4885SMN1; SMN2 4201/4885 |
| US-10696700-B2 | Charged linkers and their uses for conjugation | PHOSPHO1, PCTP, CD2BP2 | ALDH1A1 4122/4885TRPA1 4872/4885SMN1; SMN2 3710/4885 |
| US-20150250896-A1 | HYDROPHILIC LINKERS AND THEIR USES FOR CONJUGATION OF DRUGS TO A CELL BINDING MOLECULES | CD44, EPCAM, ABCG2 | ALDH1A1 1784/4885TRPA1 4847/4885SMN1; SMN2 4201/4885 |
| US-20090170813-A1 | Hypophosphorous Acid Derivatives and their Therapeutical Applications | P4HA1, CYP2R1, EGLN3 | ALDH1A1 2089/4885TRPA1 4625/4885SMN1; SMN2 2459/4885 |
| US-20190127401-A1 | CHARGED LINKERS AND THEIR USES FOR CONJUGATION | PHOSPHO1, PCTP, CD2BP2 | ALDH1A1 4122/4885TRPA1 4872/4885SMN1; SMN2 3710/4885 |
| US-20190127400-A1 | CHARGED LINKERS AND THEIR USES FOR CONJUGATION | PHOSPHO1, PCTP, CD2BP2 | ALDH1A1 4122/4885TRPA1 4872/4885SMN1; SMN2 3710/4885 |
| US-10683314-B2 | Charged linkers and their uses for conjugation | PHOSPHO1, PCTP, CD2BP2 | ALDH1A1 4122/4885TRPA1 4872/4885SMN1; SMN2 3710/4885 |
| US-10696699-B2 | Charged linkers and their uses for conjugation | PHOSPHO1, PCTP, CD2BP2 | ALDH1A1 4122/4885TRPA1 4872/4885SMN1; SMN2 3710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.