Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16601927 | 0.77 | KMT2A (0.64) | LMNAKMT2AMEN1MAPTNPSR1 | |
| SCHEMBL4099367 | 0.75 | LMNA (0.54) | LMNAKMT2AMEN1MAPTNPSR1 | |
| SCHEMBL104513 | 0.73 | GABRA1 (0.50) | LMNASLC6A2CYP1A2CYP3A4SMN1; SMN2 | |
| SCHEMBL30223644 | 0.73 | GABRA1 (0.50) | LMNASLC6A2CYP1A2CYP3A4SMN1; SMN2 | |
| SCHEMBL713707 | 0.72 | MEN1 (0.68) | LMNAKMT2AMEN1MAPTNPSR1 | |
| SCHEMBL29869345 | 0.72 | MEN1 (0.68) | LMNAKMT2AMEN1MAPTNPSR1 | |
| SCHEMBL4096798 | 0.71 | TSHR (0.50) | LMNAKMT2AMEN1MAPTNPSR1 | |
| SCHEMBL4808650 | 0.71 | GABRA1 (0.48) | LMNASLC6A2CYP1A2CYP3A4GABRA1 | |
| Bromide SCHEMBL7344099 | 0.71 | GABRA1 (0.48) | LMNASLC6A2CYP1A2CYP3A4SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2864375 | 0.71 | GABRA1 (0.48) | LMNASLC6A2CYP1A2CYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2039677-B1 | Organic compounds containing heteroatoms and their use in ziegler-natta catalyst with single activation center | SHANGHAI INST ORGANIC CHEM (CN) | 2014-04-23 | — | — | EP | disclosed |
| US-20140073500-A1 | CLASS OF ORGANIC COMPOUNDS CONTAINING HETEROATOM AND ITS APPLICATIONS IN PREPARING SINGLE-SITE ZIEGLER-NATTA CATALYST | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2014-03-13 | — | — | US | disclosed |
| US-20090137383-A1 | CLASS OF ORGANIC COMPOUNDS CONTAINING HETEROATOM AND ITS APPLICATIONS IN PREPARING SINGLE-SITE ZIEGLER-NATTA CATALYST | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2009-05-28 | — | — | US | disclosed |
| EP-2039677-A1 | ORGANIC COMPOUNDS CONTAINING HETEROATOMS AND THEIR USE IN ZIEGLER-NATTA CATALYST WITH SINGLE ACTIVATION CENTER | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2009-03-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140073500-A1 | CLASS OF ORGANIC COMPOUNDS CONTAINING HETEROATOM AND ITS APPLICATIONS IN PREPARING SINGLE-SITE ZIEGLER-NATTA CATALYST | CCNT1, SP1, CCNT2 | LMNA 1583/4885KMT2A 585/4885MEN1 676/4885 |
| US-20090137383-A1 | CLASS OF ORGANIC COMPOUNDS CONTAINING HETEROATOM AND ITS APPLICATIONS IN PREPARING SINGLE-SITE ZIEGLER-NATTA CATALYST | CCNT1, SP1, CCNT2 | LMNA 1583/4885KMT2A 585/4885MEN1 676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.