Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.64 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.64 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 2/20 | 0.37 |
| ▸ | NOS1 | P29475 | 2/20 | 0.37 |
| ▸ | NOS2 | P35228 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL944019 | 0.87 | GABRA1 (0.48) | KMT2AMEN1MAPTNPSR1APOBEC3G | |
| SCHEMBL34097 | 0.80 | MEN1 (1.00) | KMT2AMEN1MAPTNPSR1APOBEC3G | |
| SCHEMBL30063472 | 0.80 | MEN1 (1.00) | KMT2AMEN1MAPTNPSR1APOBEC3G | |
| Hydrochloric Acid SCHEMBL3248165 | 0.78 | MEN1 (0.94) | KMT2AMEN1MAPTNPSR1APOBEC3G | |
| SCHEMBL4096736 | 0.77 | LMNA (0.46) | KMT2AMEN1MAPTNPSR1APOBEC3G | |
| SCHEMBL30223644 | 0.75 | GABRA1 (0.50) | GABRA1GABRB2TDP1NOS3NOS1 | |
| SCHEMBL104513 | 0.75 | GABRA1 (0.50) | GABRA1GABRB2TDP1NOS3NOS1 | |
| SCHEMBL21032249 | 0.75 | GABRA1 (0.41) | KMT2AGABRA1GABRB2POLBNOS3 | |
| SCHEMBL10408276 | 0.74 | CYP2D6 (0.43) | KMT2AMEN1MAPTNPSR1APOBEC3G | |
| Hydrochloric Acid SCHEMBL2864375 | 0.73 | GABRA1 (0.48) | GABRA1GABRB2TDP1NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11697804-B2 | Transcriptionally targeted and CpG-free plasmid for theranostic gene therapy | THE JOHNS HOPKINS UNIVERSITY (US) | 2023-07-11 | — | — | US | disclosed |
| US-8992991-B2 | Multicomponent degradable cationic polymers | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11697804-B2 | Transcriptionally targeted and CpG-free plasmid for theranostic gene therapy | POLRMT, HDGF, PCNP | KMT2A 724/4885MEN1 1750/4885MAPT 893/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.