Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30389926 | 1.00 | GABRA1 (0.48) | GABRA1GABRB2GABRG2GABRB3FAAH | |
| SCHEMBL4800273 | 0.89 | HTR1A (0.41) | GABRA1GABRB2GABRG2GABRB3FAAH | |
| SCHEMBL2888693 | 0.86 | GABRA1 (0.41) | GABRA1GABRB2GABRG2GABRB3FAAH | |
| SCHEMBL944019 | 0.84 | GABRA1 (0.48) | GABRA1GABRB2GABRG2GABRB3FAAH | |
| SCHEMBL24499263 | 0.82 | APOBEC3G (0.52) | GABRA1GABRB2GABRG2GABRB3LMNA | |
| SCHEMBL5594562 | 0.82 | GABRA1 (0.46) | GABRA1GABRB2GABRG2GABRB3FAAH | |
| SCHEMBL5318161 | 0.81 | L3MBTL1 (0.46) | GABRA1GABRB2CYP1A2CYP3A4HPGD | |
| SCHEMBL4143745 | 0.80 | P2RX7 (0.37) | GABRA1GABRB2GABRG2GABRB3FAAH | |
| SCHEMBL588784 | 0.80 | GABRA1 (0.39) | GABRA1GABRB2GABRG2GABRB3FAAH | |
| SCHEMBL587834 | 0.80 | GABRA1 (0.34) | GABRA1GABRB2GABRG2GABRB3FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103787802-B | One class arylalkyl thioethers compound and synthetic method thereof | EAST CHINA NORMAL UNIVERSITY (CN) | 2015-08-19 | — | — | CN | disclosed |
| CN-103787802-A | Aryl alkyl thioether compounds and synthesis method thereof | UNIV EAST CHINA NORMAL | 2014-05-14 | — | — | CN | disclosed |
| US-7323608-B2 | Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-01-29 | — | — | US | disclosed |
| US-7323608-B2 | Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-01-29 | — | — | US | disclosed |
| US-7323608-B2 | Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-01-29 | — | — | US | disclosed |
| EP-1534671-A4 | COPPER-CATALYZED FORMATION OF CARBON-HETEROATOM AND CARBON-CARBON BONDS | MASSACHUSETTS INST TECHNOLOGY (US) | 2007-10-24 | — | — | EP | disclosed |
| US-20050250959-A1 | Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-11-10 | — | — | US | disclosed |
| CN-1684944-A | method for copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds | MASSACHUSETTS INST TECHNOLOGY (US) | 2005-10-19 | — | — | CN | disclosed |
| EP-1534671-A2 | COPPER-CATALYZED FORMATION OF CARBON-HETEROATOM AND CARBON-CARBON BONDS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2005-06-01 | — | — | EP | disclosed |
| US-6888032-B2 | Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2005-05-03 | — | — | US | disclosed |
| US-20040138468-A1 | Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-07-15 | — | — | US | disclosed |
| WO-2004013094-A2 | COPPER-CATALYZED FORMATION OF CARBON-HETEROATOM AND CARBON-CARBON BONDS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2004-02-12 | — | — | WO | disclosed |
| US-5164514-A | Antispasmodics | ROUSSEL UCLAF (FR) | 1992-11-17 | — | — | US | disclosed |
| US-5081130-A | Antispasmodic agents | ROUSSEL UCLAF (FR) | 1992-01-14 | — | — | US | disclosed |
| US-4990531-A | Antispasmodic agents | ROUSSEL UCLAF (FR) | 1991-02-05 | — | — | US | disclosed |
| EP-0003913-B1 | PESTICIDALLY ACTIVE BENZOPHENONE HYDRAZONE DERIVATIVES, METHODS FOR THEIR PRODUCTION AND PESTICIDAL COMPOSITIONS AND METHODS | FBC LIMITED (GB) | 1984-05-02 | — | — | EP | disclosed |
| US-4394387-A | INSECTICIDES, MITICIDES | THE BOOTS COMPANY PLC (GB) | 1983-07-19 | — | — | US | disclosed |
| US-4344893-A | SUBSTITUTED BENZOPHENONE HYDRAZONES | THE BOOTS COMPANY LIMITED (GB) | 1982-08-17 | — | — | US | disclosed |
| EP-0003913-A1 | Pesticidally active benzophenone hydrazone derivatives, methods for their production and pesticidal compositions and methods | FBC LIMITED (GB) | 1979-09-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050250959-A1 | Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds | CBR3, TST, CBS | GABRA1 2529/4885GABRB2 2102/4885GABRG2 2348/4885 |
| US-20040138468-A1 | Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds | CBR3, TST, CBS | GABRA1 2503/4885GABRB2 2125/4885GABRG2 2375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.