SCHEMBL4096877

SCHEMBL4096877

NC(=O)C[C@@H](C(=O)O)N(C(=O)OCC1c2ccccc2-c2ccccc21)C(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.40
FABP5 Q01469 3/20 0.39
FABP7 O15540 2/20 0.39
MDM4 O15151 2/20 0.37
TP53 P04637 2/20 0.37
CASP3 P42574 2/20 0.37
EPHX2 P34913 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CYP1A2 P05177 1/20 0.34
TSHR P16473 1/20 0.34
HSD17B10 Q99714 1/20 0.33
MDM2 Q00987 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21581904 1.00 KMT2A (0.40) KMT2AFABP5FABP7MDM4TP53
SCHEMBL29875636 1.00 KMT2A (0.40) KMT2AFABP5FABP7MDM4TP53
SCHEMBL30112800 1.00 KMT2A (0.40) KMT2AFABP5FABP7MDM4TP53
SCHEMBL29397011 1.00 KMT2A (0.40) KMT2AFABP5FABP7MDM4TP53
SCHEMBL25322549 0.89 KMT2A (0.38) KMT2AFABP5FABP7MDM4TP53
SCHEMBL29875681 0.89 KMT2A (0.38) KMT2AFABP5FABP7MDM4TP53
SCHEMBL5501054 0.89 KMT2A (0.38) KMT2AFABP5FABP7MDM4TP53
SCHEMBL27738280 0.89 KMT2A (0.38) KMT2AFABP5FABP7MDM4TP53
SCHEMBL8494693 0.88 FABP5 (0.41) KMT2AFABP5FABP7MDM4TP53
SCHEMBL4428638 0.87 FABP5 (0.40) KMT2AFABP5FABP7MDM4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114163354-B Preparation method of N-fluorenylmethoxycarbonyl-N-trityl-L-asparagine 常州吉恩药业有限公司 2023-05-05 CN claimed
CN-115232195-A Oligopeptide two-dimensional nanomaterial and application thereof 忻州师范学院 2022-10-25 CN claimed
CN-114948860-A Supermolecule hydrogel nano material, gelator, preparation method and application thereof 东南大学 2022-08-30 CN claimed
CN-114163354-A Preparation method of N-fluorenylmethoxycarbonyl-N-trityl-L-asparagine 常州吉恩药业有限公司 2022-03-11 CN claimed
CN-120192365-A Colipase inhibiting peptide and application thereof 宜客美股份有限公司 2025-06-24 CN disclosed
CN-114591944-B High-sensitivity HPV virus detection kit 杭州康大晨星医学科技有限公司 2025-04-04 CN disclosed
CN-118946593-A Insulin hybrid peptide containing chymotrypsin inhibitory peptide and application thereof 中国医学科学院药物研究所 2024-11-12 CN disclosed
CN-118725006-A Process for preparing insoluble peptide 南京金斯瑞生物科技有限公司 2024-10-01 CN disclosed
CN-118620022-A Process for preparing phosphorylated polypeptides 南京金斯瑞生物科技有限公司 2024-09-10 CN disclosed
CN-115073587-B Synthesis process for synthesizing bivalirudin by semi-continuous liquid phase synthesis 厦门胜泽泰医药科技有限公司 2024-08-23 CN disclosed
CN-117720621-B Alpha-amylase inhibiting peptide and application thereof 北京晶泰科技有限公司 2024-05-31 CN disclosed
CN-117736255-A Method for modifying polypeptide 江苏金斯瑞生物科技有限公司 2024-03-22 CN disclosed
WO-2013091670-A1 NOVEL JNK INHIBITOR MOLECULES FOR TREATMENT OF VARIOUS DISEASES XIGEN S.A. (CH) 2013-06-27 WO disclosed
EP-2582714-A2 NOVEL JNK INHIBITOR MOLECULES Xigen S.A. (CH) 2013-04-24 EP disclosed
WO-2011160653-A1 NOVEL JNK INHIBITOR MOLECULES XIGEN S.A. (CH) 2011-12-29 WO disclosed
WO-2011160827-A2 NOVEL JNK INHIBITOR MOLECULES XIGEN S.A. (CH) 2011-12-29 WO disclosed
US-8076285-B2 Lysobactin amides AICURIS GMBH & CO. KG (DE) 2011-12-13 US disclosed
CN-102199195-A Half-path charge matching amphiphilic self assembling short peptide, and its application as nanometer hemostatic material and hydrophobic drug carrier UNIV SOUTH CHINA TECH 2011-09-28 CN disclosed
US-20090203582-A1 LYSOBACTIN AMIDES BAYER HEALTHCARE AG (DE) 2009-08-13 US disclosed
CN-101492494-A Integrin ligand cyclic peptide analogues and cyclization method UNIV ZHEJIANG (CN) 2009-07-29 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090203582-A1 LYSOBACTIN AMIDES AADAT, HAMP, DLST KMT2A 448/4885FABP5 885/4885FABP7 2324/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.