Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2329392 | 0.83 | ALDH1A1 (0.61) | ALDH1A1KDM4EMAPTKMT2ATSHR | |
| Hydrochloric Acid SCHEMBL3727637 | 0.82 | ALDH1A1 (0.60) | ALDH1A1KDM4EMAPTKMT2ATSHR | |
| SCHEMBL4845475 | 0.81 | SMN1; SMN2 (0.51) | ALDH1A1KDM4EMAPTKMT2ATSHR | |
| SCHEMBL1436140 | 0.77 | MAPT (0.49) | ALDH1A1MAPTKMT2ATSHRMEN1 | |
| SCHEMBL2080844 | 0.77 | KDR (0.65) | ALDH1A1KDM4EMAPTKMT2ATSHR | |
| SCHEMBL1436230 | 0.76 | MAPT (0.56) | KDM4EMAPTTSHRTP53MAPK1 | |
| SCHEMBL12617388 | 0.75 | ALDH1A1 (0.58) | ALDH1A1KDM4EMAPTKMT2ATSHR | |
| SCHEMBL4844000 | 0.75 | ALDH1A1 (0.46) | ALDH1A1KDM4EMAPTKMT2ATSHR | |
| SCHEMBL4854116 | 0.75 | KDR (0.56) | ALDH1A1KDM4EMAPTKMT2ATSHR | |
| SCHEMBL5103142 | 0.75 | RXFP1 (0.52) | ALDH1A1KDM4EMAPTKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090054435-A1 | Phenoxyalkanoic Acid Compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-02-26 | — | — | US | disclosed |
| US-7368578-B2 | Five-membered heterocyclic compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-06 | — | — | US | disclosed |
| EP-1911738-A1 | PHENOXYALKANOIC ACID COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2008-04-16 | — | — | EP | disclosed |
| US-20060135578-A1 | Five-membered heterocyclic compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-06-22 | — | — | US | disclosed |
| EP-1541564-A1 | FIVE-MEMBERED HETEROCYCLIC COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2005-06-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054435-A1 | Phenoxyalkanoic Acid Compound | PNLIP, GPR119, LIPC | ALDH1A1 426/4885KDM4E 310/4885MAPT 3533/4885 |
| US-20060135578-A1 | Five-membered heterocyclic compounds | GPR119, OR10J3, CYP11B1 | ALDH1A1 821/4885KDM4E 719/4885MAPT 4700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.