Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.41 |
| ▸ | GLS | O94925 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14035363 | 1.00 | LMNA (0.45) | LMNAGAAHDAC1KDM4ESLC6A9 | |
| SCHEMBL4099573 | 1.00 | LMNA (0.45) | LMNAGAAHDAC1KDM4ESLC6A9 | |
| SCHEMBL14035298 | 0.92 | HDAC1 (0.43) | HDAC1KDM4ESLC6A9ATMSETD7 | |
| SCHEMBL28602480 | 0.88 | SLC6A9 (0.56) | SLC6A9MEN1KMT2A | |
| SCHEMBL18271394 | 0.88 | SLC6A9 (0.56) | SLC6A9MEN1KMT2A | |
| SCHEMBL18271130 | 0.88 | SLC6A9 (0.56) | SLC6A9MEN1KMT2A | |
| SCHEMBL14035361 | 0.83 | SLC6A9 (0.43) | HDAC1SLC6A9ATMSETD7MAP4K4 | |
| SCHEMBL1852622 | 0.80 | GLS (0.57) | LMNAGAAKDM4EATMGLS | |
| SCHEMBL16822486 | 0.78 | SLC6A9 (0.43) | HDAC1SLC6A9ATMSETD7MAP4K4 | |
| SCHEMBL16822525 | 0.78 | SLC6A9 (0.43) | HDAC1SLC6A9ATMSETD7MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090215778-A1 | Alpha-substituted Arylmethyl Piperazine Pyrazolo [1,5-alpha]Pyrimidine Amide Derivatives | PANACOS PHARMACEUTICALS, INC. (US) | 2009-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215778-A1 | Alpha-substituted Arylmethyl Piperazine Pyrazolo [1,5-alpha]Pyrimidine Amide Derivatives | THPO, DPYD, TPMT | LMNA 4074/4885GAA 831/4885HDAC1 210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.