SCHEMBL1852622

SCHEMBL1852622

CC(C)(C)OC(=O)N1CCN(C(C(=O)O)c2ccccc2)CC1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLS O94925 2/20 0.57
LMNA P02545 1/20 0.55
GAA P10253 1/20 0.54
ATM Q13315 1/20 0.52
GPR119 Q8TDV5 1/20 0.50
KMT2A Q03164 2/20 0.49
MEN1 O00255 1/20 0.49
MGLL Q99685 1/20 0.48
TSHR P16473 2/20 0.46
ALOX15 P16050 1/20 0.46
CKS1B P61024 1/20 0.46
SKP1 P63208 1/20 0.46
SKP2 Q13309 1/20 0.46
CHRM2 P08172 1/20 0.46
CHRM4 P08173 1/20 0.46
CHRM1 P11229 1/20 0.46
CHRM3 P20309 1/20 0.46
NPC1 O15118 1/20 0.46
ALDH1A1 P00352 1/20 0.46
MAPT P10636 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14128435 0.89 GPR119 (0.50) GLSLMNAGAAATMGPR119
SCHEMBL12371643 0.88 MEN1 (0.56) GLSKMT2AMEN1MGLLNPC1
SCHEMBL5083759 0.88 ALDH1A1 (0.61) GLSLMNAATMGPR119KMT2A
SCHEMBL5183732 0.88 MEN1 (0.49) GLSLMNAATMGPR119KMT2A
SCHEMBL19668434 0.87 ALDH1A1 (0.55) GLSLMNAGPR119KMT2AMEN1
SCHEMBL19668491 0.86 CYP3A4 (0.47) GLSLMNAGAAATMGPR119
SCHEMBL29508239 0.86 CYP3A4 (0.47) GLSLMNAGAAATMGPR119
SCHEMBL29363322 0.86 CYP3A4 (0.59) GLSGPR119MGLLCYP3A4CYP3A5
SCHEMBL19668681 0.86 CYP3A4 (0.59) GLSGPR119MGLLCYP3A4CYP3A5
SCHEMBL13476475 0.86 P2RX3 (0.48) GLSLMNAATMGPR119MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 192 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026107097-A1 SELF-IMMOLATIVE LINKERS AND CONJUGATES THEREOF ENLAZA THERAPEUTICS, INC. (US) 2026-05-21 WO disclosed
US-12630808-B2 Modified archaeal family b polymerases Singular Genomics Systems, Inc. (US) 2026-05-19 US disclosed
US-20260125660-A1 MODIFIED ARCHAEAL FAMILY B POLYMERASES SINGULAR GENOMICS SYSTEMS INC (US) 2026-05-07 US disclosed
US-20260091017-A1 TREATMENTS FOR INFLAMMATION AUCKLAND UNISERVICES LTD (NZ) 2026-04-02 US disclosed
US-20260085299-A1 ENGINEERED PYROCOCCUS ENZYMES AND USES THEREOF SINGULAR GENOMICS SYSTEMS INC (US) 2026-03-26 US disclosed
US-12564644-B2 Cyclodextrin complexes of specialized proresolving mediators THETIS PHARMACEUTICALS LLC (US) 2026-03-03 US disclosed
EP-4677087-A1 NOVEL TREATMENTS FOR OCULAR DISORDERS Glaukos Corporation (US) 2026-01-14 EP disclosed
US-20250381270-A1 ISOLATING ACTIVE T-CELL CARS FROM BULK TRANSDUCED HUMAN T-CELLS UNIV CALIFORNIA (US) 2025-12-18 US disclosed
US-20250353926-A1 CROSSLINKING MULTISPECIFIC ANTIBODIES ENLAZA THERAPEUTICS INC (US) 2025-11-20 US disclosed
US-20250352508-A1 PREVENTION AND TREATMENT OF POST-ACUTE INFECTION SYNDROMES INFLAMMX THERAPEUTICS INC (US) 2025-11-20 US disclosed
US-20040176405-A1 Methods and compounds for inhibitting MRP1 KROIN JULIAN (US) 2004-09-09 US disclosed
US-20040116699-A1 Melanocortin receptor agonists ELI LILLY AND COMPANY 2004-06-17 US disclosed
US-6743794-B2 MULTIDRUG RESISTANCE PROTEIN; CANCER; 3-(9-CHLORO-3-METHYL-4-OXO-5H-ISOXAZOLO(4,3-C)QUINOLIN-5-YL)) CYCLOHEXYL)-2-PIPERIDYLACETAMIDE ELI LILLY AND COMPANY 2004-06-01 US disclosed
EP-1358163-A1 MELANOCORTIN RECEPTOR AGONISTS ELI LILLY AND COMPANY (US) 2003-11-05 EP disclosed
US-20030153556-A1 Piperazine and homopiperazine compounds MILLENNIUM PHARMACEUTICALS, INC. 2003-08-14 US disclosed
US-20030100576-A1 Methods and compounds for inhibiting mrp1 ELI LILLY AND COMPANY 2003-05-29 US disclosed
WO-2003022214-A2 PIPERAZINE AND HOMOPIPERAZINE COMPOUNDS MILLENNIUM PHARMACEUTICALS, INC. (US) 2003-03-20 WO disclosed
EP-1250340-A1 METHODS AND COMPOUNDS FOR INHIBITING MRP1 ELI LILLY AND COMPANY (US) 2002-10-23 EP disclosed
WO-2002059095-A1 MELANOCORTIN RECEPTOR AGONISTS ELI LILLY AND COMPANY (US) 2002-08-01 WO disclosed
WO-2001046199-A1 METHODS AND COMPOUNDS FOR INHIBITING MRP1 ELI LILLY AND COMPANY (US) 2001-06-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260091017-A1 TREATMENTS FOR INFLAMMATION P2RX7, NLRP3, PYCARD GLS 3210/4885LMNA 880/4885GAA 4329/4885
US-20250352508-A1 PREVENTION AND TREATMENT OF POST-ACUTE INFECTION SYNDROMES NLRP3, GJA1, PYCARD GLS 1719/4885LMNA 40/4885GAA 3430/4885
US-12630808-B2 Modified archaeal family b polymerases SSU72, POLB, POLQ GLS 226/4885LMNA 547/4885GAA 3345/4885
US-20030153556-A1 Piperazine and homopiperazine compounds HAMP, MPL, F2 GLS 1814/4885LMNA 4352/4885GAA 4771/4885
US-20250381270-A1 ISOLATING ACTIVE T-CELL CARS FROM BULK TRANSDUCED HUMAN T-CELLS PBK, CD4, ICOS GLS 3670/4885LMNA 3021/4885GAA 1458/4885
US-20250353926-A1 CROSSLINKING MULTISPECIFIC ANTIBODIES FCGR3B, FCGR2A, CD22 GLS 1050/4885LMNA 3532/4885GAA 898/4885
US-20040176405-A1 Methods and compounds for inhibitting MRP1 ABCC1, ABCB11, ABCB1 GLS 118/4885LMNA 2547/4885GAA 763/4885
US-20260085299-A1 ENGINEERED PYROCOCCUS ENZYMES AND USES THEREOF POLB, POLM, POLRMT GLS 309/4885LMNA 1840/4885GAA 3036/4885
US-20030100576-A1 Methods and compounds for inhibiting mrp1 ABCC1, ABCB11, ABCB1 GLS 96/4885LMNA 2226/4885GAA 806/4885
US-20260125660-A1 MODIFIED ARCHAEAL FAMILY B POLYMERASES DNMT3A, POLB, POLM GLS 246/4885LMNA 1601/4885GAA 3263/4885
US-12564644-B2 Cyclodextrin complexes of specialized proresolving mediators ALOX15, ALOX12, PTGES GLS 3937/4885LMNA 1120/4885GAA 4780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.