Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL4097380

COc1ccc(C(=O)c2ccc(OCc3ccc(OC(F)(F)F)c(Cl)c3)nc2)c(OC(C)(C)C(=O)O)c1.O=C(O)C(F)(F)F

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 13/20 0.43
PPARD Q03181 12/20 0.43
PPARG P37231 10/20 0.43
PTGDR2 Q9Y5Y4 1/20 0.40
MRGPRX4 Q96LA9 2/20 0.39
VNN1 O95497 1/20 0.37
ALOX5AP P20292 1/20 0.37
SCN1A P35498 1/20 0.36
SCN9A Q15858 1/20 0.36
SCN2A Q99250 1/20 0.36
SCN3A Q9NY46 1/20 0.36
SCN10A Q9Y5Y9 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4097382 0.91 PTGDR2 (0.38) PPARAPPARDPPARGPTGDR2MRGPRX4
SCHEMBL4092277 0.89 PPARG (0.48) PPARAPPARDPPARGPTGDR2MRGPRX4
Trifluoroacetic Acid SCHEMBL4100117 0.88 NPC1 (0.38) PPARAPPARDPPARG
Trifluoroacetic Acid SCHEMBL4103434 0.87 PPARG (0.45) PPARAPPARDPPARGMRGPRX4
Trifluoroacetic Acid SCHEMBL4102682 0.85 PPARD (0.42) PPARAPPARDPPARGMRGPRX4
Trifluoroacetic Acid SCHEMBL4102425 0.84 EPHX2 (0.42) PPARAPPARDPPARG
Trifluoroacetic Acid SCHEMBL4100244 0.83 MAPT (0.39) PPARAPPARDPPARG
Trifluoroacetic Acid SCHEMBL4098182 0.82 PPARG (0.41) PPARAPPARDPPARG
Trifluoroacetic Acid SCHEMBL4093275 0.81 PPARG (0.47) PPARAPPARDPPARG
Trifluoroacetic Acid SCHEMBL4103725 0.80 PPARA (0.40) PPARAPPARDPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090054435-A1 Phenoxyalkanoic Acid Compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-02-26 US disclosed
EP-1911738-A1 PHENOXYALKANOIC ACID COMPOUND Takeda Pharmaceutical Company Limited (JP) 2008-04-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054435-A1 Phenoxyalkanoic Acid Compound PNLIP, GPR119, LIPC PPARA 8/4885PPARD 30/4885PPARG 23/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.