Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL4100117

COc1ccc(C(=O)c2ccc(OCc3cc(Cl)cc(Cl)c3)nc2)c(OC(C)(C)C(=O)O)c1.O=C(O)C(F)(F)F

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.38
PPARG P37231 11/20 0.38
PPARA Q07869 7/20 0.38
PPARD Q03181 7/20 0.38
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
FABP2 P12104 1/20 0.37
SLC22A12 Q96S37 1/20 0.37
POLB P06746 2/20 0.36
LTC4S Q16873 1/20 0.36
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL4103434 0.91 PPARG (0.45) NPC1PPARGPPARAPPARDTDP1
SCHEMBL4100119 0.90 NPC1 (0.37) NPC1TDP1L3MBTL1POLBLTC4S
Trifluoroacetic Acid SCHEMBL4102682 0.90 PPARD (0.42) NPC1PPARGPPARAPPARDPOLB
Trifluoroacetic Acid SCHEMBL4097380 0.88 PPARA (0.43) PPARGPPARAPPARD
Trifluoroacetic Acid SCHEMBL4102425 0.88 EPHX2 (0.42) NPC1PPARGPPARAPPARDTDP1
SCHEMBL4108605 0.86 PPARG (0.51) NPC1PPARGPPARAPPARDTDP1
Trifluoroacetic Acid SCHEMBL4100244 0.85 MAPT (0.39) NPC1PPARGPPARAPPARDTDP1
Trifluoroacetic Acid SCHEMBL4093275 0.83 PPARG (0.47) PPARGPPARAPPARDTDP1
Trifluoroacetic Acid SCHEMBL4103725 0.83 PPARA (0.40) NPC1PPARGPPARAPPARDL3MBTL1
Trifluoroacetic Acid SCHEMBL4099638 0.82 POLB (0.41) NPC1PPARGPPARAPPARDTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090054435-A1 Phenoxyalkanoic Acid Compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-02-26 US disclosed
EP-1911738-A1 PHENOXYALKANOIC ACID COMPOUND Takeda Pharmaceutical Company Limited (JP) 2008-04-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054435-A1 Phenoxyalkanoic Acid Compound PNLIP, GPR119, LIPC NPC1 170/4885PPARG 23/4885PPARA 8/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.