SCHEMBL4098529

SCHEMBL4098529

CC(=O)CC(=O)OC(=O)CC/C(=N/O)OC(=O)CC(C)=O

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.41
GAA P10253 1/20 0.41
SI P14410 1/20 0.41
MGAM2 Q2M2H8 1/20 0.41
ALDH1A1 P00352 1/20 0.37
TSHR P16473 1/20 0.34
KDM4E B2RXH2 1/20 0.31
LMNA P02545 1/20 0.31
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19283437 0.83 MGAM (0.57) MGAMGAASIMGAM2ALDH1A1
SCHEMBL731664 0.82 ALDH1A1 (0.46) ALDH1A1TSHR
SCHEMBL733088 0.80 ALDH1A1 (0.62) ALDH1A1TSHR
SCHEMBL5785545 0.78 ALDH1A1 (0.38) ALDH1A1TSHR
SCHEMBL5968591 0.78 EGLN1 (0.39) ALDH1A1TSHRKDM4ELMNA
SCHEMBL8909532 0.77 ALDH1A1 (0.37) ALDH1A1TSHR
SCHEMBL1820175 0.77 ALDH1A1 (0.33) ALDH1A1
SCHEMBL1972716 0.77 ALDH1A1 (0.33) ALDH1A1
SCHEMBL942008 0.76 ALDH1A1 (0.34) ALDH1A1
SCHEMBL1768486 0.76 ALDH1A1 (0.34) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0527186-A4 UNIV ILLINOIS (US) 1995-01-18 EP claimed
EP-0527186-A1 PHOTODYNAMIC PLANT DEFOLIANTS AND CHLOROPHYLL BIOSYNTHESIS MODULATORS The Board of Trustees for the University of Illinois (US) 1993-02-17 EP claimed
WO-1991016820-A1 PHOTODYNAMIC PLANT DEFOLIANTS AND CHLOROPHYLL BIOSYNTHESIS MODULATORS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 1991-11-14 WO claimed
US-20250002531-A1 PROCESSES FOR PREPARING PHARMACEUTICALLY RELEVANT PEPTIDES STEALTH BIOTHERAPEUTICS INC. (US) 2025-01-02 US disclosed
US-12037414-B2 Processes for preparing pharmaceutically relevant peptides STEALTH BIOTHERAPEUTICS INC. (US) 2024-07-16 US disclosed
EP-3800192-A1 PROCESSES FOR PREPARING PHARMACEUTICALLY RELEVANT PEPTIDES Stealth Biotherapeutics Corp (MC) 2021-04-07 EP disclosed
US-10935544-B2 Glycan arrays and method of use OBI PHARMA, INC. (TW) 2021-03-02 US disclosed
EP-3265109-B1 PROCESSES FOR PREPARING PHARMACEUTICALLY RELEVANT PEPTIDES STEALTH BIOTHERAPEUTICS CORP (MC) 2020-10-21 EP disclosed
US-20200308221-A1 PROCESSES FOR PREPARING PHARMACEUTICALLY RELEVANT PEPTIDES STEALTH BIOTHERAPEUTICS CORP (MC) 2020-10-01 US disclosed
US-10633415-B2 Processes for preparing pharmaceutically relevant peptides STEALTH BIOTHERAPEUTICS CORP (MC) 2020-04-28 US disclosed
EP-3344806-A1 GLYCAN ARRAYS AND METHOD OF USE OBI Pharma, Inc. (TW) 2018-07-11 EP disclosed
US-20030099945-A1 Parallel selex INVENUX, INC. (US) 2003-05-29 US disclosed
EP-1115887-A4 PARALLEL SELEX INVENUX INC (US) 2002-07-17 EP disclosed
US-20020045679-A1 Aqueous ink composition HITACHI MAXELL, LTD. (JP) 2002-04-18 US disclosed
EP-1115887-A1 PARALLEL SELEX Invenux, Inc. (US) 2001-07-18 EP disclosed
US-6048698-A PRODUCING PRODUCTS BY BOND FORMATION OF A REACTANT BOUND TO NUCLEIC ACID AND A FREE REACTANT, THEN CONTACTING PRODUCT LIBRARY WITH TARGET TO PARTITION PRODUCTS BY ABILITY TO PERFORM PRESELECTED FUNCTION NEXSTAR PHARMACEUTICALS, INC. (US) 2000-04-11 US disclosed
WO-2000017398-A1 PARALLEL SELEX INVENUX, INC. (US) 2000-03-30 WO disclosed
US-5858660-A FORMING PRODUCT LIBRARY BY CONTACTING TWO OR MORE REACTANTS WHERE ONE REACTANT IS COUPLED TO NUCLEIC ACID CAPABLE OF MEDIATING BOND FORMATION, SELECTING PRODUCTS HAVING PREDETERMINED CHARACTERISTICS NEXSTAR PHARMACEUTICLAS, INC. (US) 1999-01-12 US disclosed
US-5244762-A Polymers of hydroxyacrylic amides and hydroxyacrylic esters, hydroxy group modified to become ether, ester, sulfonate, carbamate XEROX CORPORATION (US) 1993-09-14 US disclosed
US-5242892-A With 5-aminolevulinic acid THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 1993-09-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10633415-B2 Processes for preparing pharmaceutically relevant peptides ADM2, VIP, PEPD MGAM 1502/4885GAA 1903/4885SI 382/4885
US-20250002531-A1 PROCESSES FOR PREPARING PHARMACEUTICALLY RELEVANT PEPTIDES ADM2, VIP, PEPD MGAM 1502/4885GAA 1903/4885SI 382/4885
US-20030099945-A1 Parallel selex SELE, MTREX, NSUN3 MGAM 1248/4885GAA 2607/4885SI 1650/4885
US-20200308221-A1 PROCESSES FOR PREPARING PHARMACEUTICALLY RELEVANT PEPTIDES ADM2, VIP, PEPD MGAM 1502/4885GAA 1903/4885SI 382/4885
US-12037414-B2 Processes for preparing pharmaceutically relevant peptides ADM2, VIP, PEPD MGAM 1502/4885GAA 1903/4885SI 382/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.