SCHEMBL1768486

SCHEMBL1768486

O=C(CI)OC(=O)CC/C(=N/O)OC(=O)CI

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5580355 0.82 ALDH1A1 (0.48) ALDH1A1
SCHEMBL731664 0.81 ALDH1A1 (0.46) ALDH1A1
SCHEMBL5968591 0.81 EGLN1 (0.39) ALDH1A1
SCHEMBL733088 0.79 ALDH1A1 (0.62) ALDH1A1
SCHEMBL781568 0.79 ALDH1A1 (0.34) ALDH1A1
SCHEMBL942008 0.79 ALDH1A1 (0.34) ALDH1A1
SCHEMBL10972290 0.79 ALDH1A1 (0.34) ALDH1A1
SCHEMBL6738571 0.78 ALDH1A1 (0.33) ALDH1A1
SCHEMBL4098529 0.76 MGAM (0.41) ALDH1A1
SCHEMBL5069484 0.76 LMNA (0.42) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111565707-A Devices and methods for delivering therapeutics 森玛治疗公司 2020-08-21 CN claimed
US-20050059137-A1 Bio-support and preparing method of the same MACROGEN INC. (KR) 2005-03-17 US claimed
WO-2002033412-A1 BIO-SUPPORT AND PREPARING METHOD OF THE SAME MACROGEN INC. (KR) 2002-04-25 WO claimed
EP-4629967-A1 PERFLUORINATED MICELLES AND MEDICAL USES THEREOF Commissariat à l'Energie Atomique et aux Energies Alternatives (FR) 2025-10-15 EP disclosed
WO-2024121267-A1 PERFLUORINATED MICELLES AND MEDICAL USES THEREOF. COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2024-06-13 WO disclosed
EP-4382091-A1 PERFLUORINATED MICELLES AND MEDICAL USES THEREOF Commissariat à l'Energie Atomique et aux Energies Alternatives (FR) 2024-06-12 EP disclosed
CN-117405878-B Silica microsphere compound and preparation method and application thereof 上海领检科技有限公司 2024-06-11 CN disclosed
US-11905323-B2 Recombinant chimeric protein for selectins targeting Bracco Suisse (CH) 2024-02-20 US disclosed
CN-117405878-A Silica microsphere compound and preparation method and application thereof 上海领检科技有限公司 2024-01-16 CN disclosed
US-20220389080-A1 RECOMBINANT CHIMERIC PROTEIN FOR SELECTINS TARGETING BRACCO SUISSE SA (CH) 2022-12-08 US disclosed
US-11370826-B2 Recombinant chimeric protein for selectins targeting BRACCO SUISSE SA (CH) 2022-06-28 US disclosed
US-5719271-A HYBRIDS; GENETIC ENGINEERING ISIS PHARMACEUTICALS, INC. (US) 1998-02-17 US disclosed
WO-1998005687-A1 MONOCLONAL ANTIBODY WHICH AGGLUTINATES E. COLI HAVING THE CS4-CFA/I FAMILY PROTEIN DEPARTMENT OF THE ARMY, US GOVERNMENT (US) 1998-02-12 WO disclosed
EP-0733066-A1 PRETARGETING METHODS AND COMPOUNDS NEORX CORPORATION (US) 1996-09-25 EP disclosed
US-5543507-A BONDING STRANDS OR ONE STRAND AT DIFFERENT SITES; RNA MIMICS FIXED IN SPATIAL CONFORMATION; NUCLEASE RESISTANT MIMICS OF BINDING RECEPTORS FOR NUCLEIC ACID-BINDING PROTEINS; 5-LIPOXYGENASE INHIBITORS; DIAGNOSIS; ANALYZING ISIS PHARMACEUTICALS, INC. (US) 1996-08-06 US disclosed
EP-0661979-A4 CROSS-LINKING OLIGONUCLEOTIDES FOR ENZYME-MEDIATED TRIPLE STRAND FORMATION. MICROPROBE CORP (US) 1995-09-13 EP disclosed
EP-0661979-A1 CROSS-LINKING OLIGONUCLEOTIDES FOR ENZYME-MEDIATED TRIPLE STRAND FORMATION MICROPROBE CORPORATION (US) 1995-07-12 EP disclosed
WO-1995015979-A1 PRETARGETING METHODS AND COMPOUNDS NEORX CORPORATION (US) 1995-06-15 WO disclosed
WO-1993003736-A1 CROSS-LINKING OLIGONUCLEOTIDES FOR ENZYME-MEDIATED TRIPLE STRAND FORMATION MICROPROBE CORPORATION (US) 1993-03-04 WO disclosed
US-5095097-A Diagnostics BEHRINGWERKE AKTIENGESELLSCHAFT (DE) 1992-03-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11905323-B2 Recombinant chimeric protein for selectins targeting SELPLG, SELL, SELE ALDH1A1 2114/4885
US-20220389080-A1 RECOMBINANT CHIMERIC PROTEIN FOR SELECTINS TARGETING SELPLG, SELL, SELE ALDH1A1 2114/4885
US-20050059137-A1 Bio-support and preparing method of the same EPCAM, STUB1, BST2 ALDH1A1 31/4885
US-11370826-B2 Recombinant chimeric protein for selectins targeting SELPLG, SELL, SELE ALDH1A1 2114/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.