SCHEMBL4099013

SCHEMBL4099013

COc1ccc(C(=O)c2ccc(OCc3nc(-c4ccco4)oc3C)cc2)c(OC(C)(C)C(=O)O)c1

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.47
PPARG P37231 13/20 0.46
PPARA Q07869 12/20 0.46
TP53 P04637 2/20 0.44
POLB P06746 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4103807 0.89 PPARA (0.58) MAPTPPARGPPARATP53POLB
SCHEMBL4097135 0.83 MAPT (0.49) MAPTPPARGPPARATP53POLB
SCHEMBL4107292 0.81 PPARA (0.69) PPARGPPARA
SCHEMBL4755678 0.80 MAPT (0.57) MAPTPPARGPPARATP53POLB
SCHEMBL4109852 0.76 MAPT (0.61) MAPTPPARGPPARATP53POLB
SCHEMBL4092427 0.76 MAPT (0.61) MAPTPPARGPPARATP53POLB
SCHEMBL4107394 0.76 PPARG (0.63) PPARGPPARAPOLB
SCHEMBL4096147 0.76 PPARG (0.49) MAPTPPARGPPARAPOLB
SCHEMBL4102445 0.76 PPARA (0.49) MAPTPPARGPPARAPOLB
SCHEMBL4108188 0.76 PPARG (0.51) PPARGPPARAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090054435-A1 Phenoxyalkanoic Acid Compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-02-26 US disclosed
EP-1911738-A1 PHENOXYALKANOIC ACID COMPOUND Takeda Pharmaceutical Company Limited (JP) 2008-04-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054435-A1 Phenoxyalkanoic Acid Compound PNLIP, GPR119, LIPC MAPT 3533/4885PPARG 23/4885PPARA 8/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.